Article Per Year (5 Year)
p-Index From 2020 - 2025
0.408
P-Index
This Author published in this journals
All Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML)
Liong Boy Kuniawan
Department of Clinical Pathology, Faculty of Medicine of Hasanuddin University/Dr. Wahidin Sudirohusodo Hospital, Makassar
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Analysis of Serum Uric Acid Level in Patients with and without Diabetic Nephropathy Erika Rosaria Simbolon; Suci Aprianti; Nurahmi Nurahmi; Liong Boy Kuniawan
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 27, No 1 (2020)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v27i1.1594

Abstract

Diabetic nephropathy is one of the microvascular complications in type 2 Diabetes Mellitus (DM). Diagnosis of diabeticnephropathy is based on any history of DM, a decrease in Glomerular Estimation Filtrate Rate (eGFR) using the CKD-Epiformula, and albuminuria. The role of serum uric acid level in diabetic nephropathy remains an ongoing debate. Serum uricacid levels may be the cause or the result of diabetic nephropathy. This study aimed to analyze serum uric acid levels inpatients with and without diabetic nephropathy and determine its correlation with diabetic nephropathy. This study wasperformed at Dr. Wahidin Sudirohusodo Hospital, Makassar, by taking the data from the medical record of type 2 DMpatients from January to April 2018. Fifty-nine patients with diabetic nephropathy and 150 patients without diabeticnephropathy participated in this study. An independent T-test and Pearson's correlation test were used for statisticalanalysis. There was a significant difference in uric acid level between patients with and without diabetic nephropathy(9.57±3.42 mg/dL vs. 6.41±2.86 mg/dL, p < 0.001). There was significant correlation between uric acid serum levels with urea(p < 0.001, r=0.585), creatinine (p<0.001, r=0.413) and eGFR (p < 0.001, r=-0.525) in patients with diabetic nephropathy. Uricacid levels in patients with diabetic nephropathy were higher than patients without diabetic nephropathy. Higher levels ofurea and the serum creatinine led to higher levels of serum uric acid. Contrastingly, a lower eGFR rate led to higher levels ofuric acid.
Analysis of Serum Uric Acid Level in Patients with and without Diabetic Nephropathy Erika Rosaria Simbolon; Suci Aprianti; Nurahmi Nurahmi; Liong Boy Kuniawan
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 27 No. 1 (2020)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v27i1.1594

Abstract

Diabetic nephropathy is one of the microvascular complications in type 2 Diabetes Mellitus (DM). Diagnosis of diabetic nephropathy is based on any history of DM, a decrease in Glomerular Estimation Filtrate Rate (eGFR) using the CKD-Epi formula, and albuminuria. The role of serum uric acid level in diabetic nephropathy remains an ongoing debate. Serum uric acid levels may be the cause or the result of diabetic nephropathy. This study aimed to analyze serum uric acid levels in patients with and without diabetic nephropathy and determine its correlation with diabetic nephropathy. This study was performed at Dr. Wahidin Sudirohusodo Hospital, Makassar, by taking the data from the medical record of type 2 DM patients from January to April 2018. Fifty-nine patients with diabetic nephropathy and 150 patients without diabetic nephropathy participated in this study. An independent T-test and Pearson's correlation test were used for statistical analysis. There was a significant difference in uric acid level between patients with and without diabetic nephropathy (9.57±3.42 mg/dL vs. 6.41±2.86 mg/dL, p < 0.001). There was significant correlation between uric acid serum levels with urea (p < 0.001, r=0.585), creatinine (p<0.001, r=0.413) and eGFR (p < 0.001, r=-0.525) in patients with diabetic nephropathy. Uric acid levels in patients with diabetic nephropathy were higher than patients without diabetic nephropathy. Higher levels of urea and the serum creatinine led to higher levels of serum uric acid. Contrastingly, a lower eGFR rate led to higher levels of uric acid.
Co-Authors Erika Rosaria Simbolon Nurahmi Nurahmi Suci Aprianti