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PENGARUH PEMBERIAN EKSTRAK ETANOL BUAH NAGA PUTIH Hylocereus undatus (Haw.) Britt.&Rose TERHADAP PENURUNAN KADAR KOLESTEROL MINYAK HEWANI SECARA IN VITRO INFLUENCE OF EXTENDING WHITE DRAGON FRUIT ETHANOL EXTRACT Hylocereus undatus (Haw.) Britt. & Rose TO DECREASE IN CONCENTRATION OF CHOLESTEROL ANIMAL OIL IN VITRO Agus Suprijono; Ika Yunitasari; Achmad Wildan
BORNEO JOURNAL OF PHARMASCIENTECH Vol 3 No 1 (2019): Borneo Journal of Pharmascientech
Publisher : Sekolah Tinggi Ilmu Kesehatan Borneo Lestari Banjarbaru

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Abstract

ABSTRAK Makanan berlemak berbahaya bagi tubuh karena mengandung kolesterol tinggi dan dapat beresiko menimbulkan penyakit yang berbahaya serta dapat menimbulkan kematian. Kolesterol adalah zat alamiah dengan sifat fisik serupa lemak. Keberadaan kolesterol dibutuhkan oleh tubuh tetapi dalam keadaan berlebih akan merugikan. Buah naga mempunyai kandungan seperti zat besi, vitamin B1, B2, B3 dan C. Buah naga juga kaya akan serat, yang dibutuhkan tubuh untuk menurunkan kadar kolesterol dalam darah dan menetralkan racun dalam darah. Tujuan dari penelitian ini untuk mengetahui pengaruh pemberian ekstrak etanol buah naga putih Hylocereus undatus (Haw.) Britt.&Rose terhadap penurunan kadar kolesterol, mengetahui konsentrasi yang paling besar dalam menurunkan kadar kolesterol. Metode yang digunakan dalam penelitian ini adalah metode sokhletasi dengan menggunakan pelarut etanol. Ekstrak etanol buah naga putih dibuat dalam 5 konsentrasi (1%, 2%, 3%, 4%, 5%). Analisis konsentrasi kolesterol dilakukan dengan menggunakan metode Lieberman-Burchard. Berdasarkan hasil penelitian ekstrak etanol buah naga Hylocereus undatus (Haw.) Britt.&Rose dapat menurunkan kadar kolesterol. Persentase penurunan kadar kolesterol pada pemberian ekstrak etanol buah naga dengan metode sokhletasi didapat konsentrasi 1%, 2%, 3%, 4%, 5% sebesar 14,80%, 21,79%, 30,21%, 37,96%, 41,50%. Penurunan kadar kolesterol yang paling besar ditunjukkan pada konsentrasi 5% sebesar 41,50%. Pengaruh konsentrasi ekstrak etanol buah naga berpengaruh secara signifikan terhadap kadar kolesterol. Kata kunci : kolesterol, buah naga putih, metode Lieberman-Burchard, sokhletasi ABSTRACT Fatty foods are harmful for the body because of the high cholesterol and may be can risk of incurring diseases that are dangerous and can cause death. Cholesterol is a natural substance with similar physical properties of fat. The presence of cholesterol is needed by the body but in a condition of exceed it will be detrimental. Dragon fruit has contain such as iron contain, vitamin B1, B2, B3 and C. Dragon fruit is also rich of fiber, which is needed the body to decrease cholesterol concentration in the blood and neutralizes toxins in the blood. The purpose of this research is determinanting the effect of extending White dragon fruit ethanol extract Hylocereus undatus (Haw.) Britt.&Rose to decrease cholesterol concentration, finding the greatest concentration which can decrease cholesterol levels. The research used soxhletasi method using ethanol solvent. White dragon fruit ethanol extract prepared in 5 concentrations (1%, 2%, 3%, 4%, 5%). Analysis of the concentration of cholesterol used Lieberman-Burchard method. Based on the results of research White dragon fruit ethanol extract Hylocereus undatus (Haw.) Britt.&Rose can decrease cholesterol concentration. The Percentage of decrease cholesterol concentration with extending White dragon fruit ethanol extract by soxhletasi method obtainable concentrations are 1%, 2%, 3%, 4%, 5% can cause 14,80%, 21,79%,%,% 30,21 37,96, 41,50%. the greatest concentration which can decrease cholesterol concentration shown in the concentration of 5% can cause 41,50%. Dragon fruit ethanol extract concentration significantly influence cholesterol concentration. Keywords: cholesterol, white dragon fruit, Lieberman-Burchard method, soxhletasi.
Comparison of Thiamine Contain in Mung Beans (Vigna radiata L.) and Soybean (Glycine max (L.) Mer.) with Fresh and Boiled Treatment Agus Suprijono; Yuni Utami
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 3 No 1 (2020)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v3i1.13896

Abstract

Mung beans (Vigna radiata L.) and soybeans (Glycine max (L.) Mer.) are species of nuts that contain good nutrients for health, such as thiamine or vitamin B1. Thiamine can increase appetite and important in nervous system. Both species of beans can be processed into consumable sprouts, both fresh and boiled. The research aims to compare the concentrations of thiamine in mung beans sprouts and soybeans sprouts in fresh and boiled conditions. The research procedure began with prepared fresh and boiled samples. Boiled samples were prepared by boiled sprouts for 3 minutes at 100°C. Thiamine was extracted from samples used 0,1 N HCl by heated on a water bath at 100°C for 30 minutes. The extracts of fresh and boiled sprouts were analyzed qualitatively used chemical reagents and quantitatively used spectrophotometer UV-Vis. Qualitative analysis showed that both fresh and boiled mung beans sprouts and soybeans sprouts contain thiamine. Quantitative test results for boiled and fresh mung beans sprouts were 0,26% and 0,15%, while soybeans were 0,64% and 0,44%, respectively. The thiamine content in soybeans sprouts is higher than in mung beans sprouts. Decrease of thiamine concentration in mung beans sprouts was higher at 42,31%, for boiled sample than soybeansbenas sprouts at 31,25%. The results of statistical tests used the t test showed a significant difference in thiamine concentration between fresh and boiled beans, both mung beans and soybeans.