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All Journal Jurnal Kesehatan Islam : Islamic Health Journal Jurnal Kedokteran Komunitas (Journal of Community Medicine)
Silvy Amalia Falyani
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Environmental Science Immunology & microbiology Medicine & Pharmacology Public Health

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Uji Potensi Antioksidan Kumis Kucing (Orthosiphon aristatus) dengan Pendekatan In Vitro dan In Silico Dian Novita W; Silvy Amalia Falyani
Jurnal Kesehatan Islam : Islamic Health Journal Vol 10, No 2 (2021): Jurnal Kesehatan Islam : Islamic Health Journal
Publisher : Publikasi oleh Fakultas Kedokteran Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jki.v10i2.13823

Abstract

Abstract: Orthosiphon aristatus is a potential herb as a source of antioxidants. It is known from previous research, that the active compounds O.aristatus include eupatorin, rosmarinic acid and sinensetin. The study of the potential approach of active compounds extracts O.aristatus with the in vitro methods DPPH (1,1-Difenil-2-Pikrilhidrazil) and in silico using the help of pyrex autodock vina software, with the help of visualization using biovia discovery studio and pymol. Results obtained from in vitro tests using DPPH showed the presence of antioxidant activity with yellow spotting markers against a purple background. Studies in silico show that O.aristatus extract is potentially an antioxidant compound, this is demonstrated through the presence of ligand bonds with glutathione peroksidase (GPX) receptors namely van der Waals bonds, hydrogen bonds and several other bonds.
Peran Kendali Glukosa terhadap Indeks Massa Tubuh dan Lingkar Lengan Atas pada Pasien Diabetes Mellitus Tipe 2 di Malang Raya Sukosari Devantari; Silvy Amalia Falyani; Rahma Triliana
Jurnal Kedokteran Komunitas Vol 8, No 2 (2020)
Publisher : Jurnal Kedokteran Komunitas (Journal of Community Medicine)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (418.7 KB)

Abstract

Background: Diabetes Mellitus (DM) is a degenerative disease caused by impaired insulin function, marked by hyperglycemia. Chronic hyperglycemia may decrease the nutritional status of DM patients by measuring Body Mass ndex (BMI) and Upper Arm Circumference (UAC). This study aimed to look at the role of glucose control in BMI and UAC in Type 2 DM patients.Methods: This reserach was cross sectional studies. The respondents are male and female of diabetic patients without complications over the age of 40 years. The subjects were divided into the controlled group and uncontrolled group. Each group performed weight measurements with weight scale, body height with microtoise and UAC with a measuring tape. Independent T-Test was used to analyze the data , followed by a Pearson correlation test with a significance level of p<0.05.Results: There was no significant difference between glucose control, BMI (p=0.921), right UAC (p=0.611) and left UAC (p=0.406) in controlled group and uncontrolled group. Glucose control had no correlation to BMI (r=-0.061). There was also no correlation between glucose control, right UAC (r=0.161) and left UAC (r=0.197).Conclusion: Glucose control had no role in body mass index and upper arm circumference towards patients with diabetes mellitus type 2 in Malang.Keywords: Glucose control, body mass index, upper arm circumference, type 2 diabetes mellitus
Co-Authors Dian Novita W Rahma Triliana Sukosari Devantari