Paulina Maya Octasari
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Evaluasi Kelengkapan Administratif dan Farmasetis Resep di Poliklinik Anak Rumah Sakit Karanggede Sisma Medika Boyolali Paulina Maya Octasari; Patriana Agustin Windasari
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 1 No. 2 (2022): Oktober: Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v1i2.8

Abstract

Prescription screening is one of the pharmaceutical services carried out by reviewing prescriptions according to administrative, pharmaceutical and clinical requirements. Administrative and pharmaceutical requirements ensure the legality of prescriptions, correct identification and successful treatment of patients. The purpose of this study was to evaluate the administrative and pharmaceutical completeness of prescriptions at the Children's Polyclinic Karanggede Sisma Medika Hospital Boyolali. This research was carried out in an observational descriptive manner with retrospective data from prescriptions at the Children's Polyclinic at Karanggede Sisma Medika Boyolali Hospital for the period July – September 2021, with a total sample of 215 prescription sheets. The complete administrative prescription data includes the patient's name, medical record number, gender, date of birth, doctor's name, doctor's initials and date of prescription. Complete prescription pharmaceutical data include the name of the drug, the dosage form, the strength of the preparation, the dosage unit, the amount of the drug, the rules for use and how to use it. The data were analyzed quantitatively to determine the percentage of administrative completeness, pharmaceutical completeness, and both. The study was conducted with 215 prescriptions. The results of this study showed that 43.72% of prescriptions were administratively complete which consisted of 100% of the patient's names. As many as 60% are complete pharmaceutically consisting of the name of the drug, the form of the drug and the amount of the drug by 100%, and 28.37% complete both.
Uji Daya Antiinflamasi Ekstrak Etanolik Daun Mengkudu (Morinda Citrifolia (L.)) Terhadap Mencit Putih (Mus Musculus) Jantan Galur Swiss Yang Diinduksi Karagenin Paulina Maya Octasari; Andreas Napoleon
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 1 No. 2 (2022): Oktober: Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v1i2.9

Abstract

Inflammation is the body's response to protect it self from chemicals, infectious agents, and damage to body tissues caused by injury. Flavonoid compounds can be used as anti-inflammatory by inhibiting the activity of cyclooxygenase (COX) and lipoxygenase enzymes. The amount of flavonoid content in noni leaves was 15.97 mg QE/g extract. The difference between this study and the previous research conducted by Rifaldy, et al (2019) lies in the test animals, the method of measuring inflammation, and the dose of extract used. This study aims to determine the anti-inflammatory power and dosage of the ethanolic extract of noni (Morinda citrifolia (L.)) leaves. This study is an experimental study, using a completely randomized design with one-way pattern with one treatment factor, namely variations in the dose of Noni Leaf Ethanolic Extract (EEDM), namely 42 mg/20gBW mice, 56 mg/20gBW mice, and 70 mg/20gBW mice. The anti- inflammatory test method uses artificial edema formation with carrageenin. The research data was in the form of percentage of anti-inflammatory power (%DAI), thenstatistically analyzed using SPSS with 95% confidence level. The results of the anti-inflammatory power of EEDM from the smallest to the largest doses produced anti-inflammatory properties, namely 55.30%, 62.28%, and 69.41%, this means that the larger the dose, the higher the percentage of anti-inflammatory power (p<0.05). The percentage of anti-inflammatory power of EEDM at a dose of 70 mg/20gBW mice had an anti-inflammatory effect that was not significantly different from the positive control (p>0.05).