This paper explored the relationship of rural-urban migration to the total agricultural output in the Philippines. The researchers wanted to know if there is a relationship between the independent variables: rural-urban migration, average agricultural wage, number of employed people in agriculture, and inflation rate, and the dependent variable, which is agricultural output, and how these explanatory variables affect the dependent variable. Data used are from the years 1988 - 2018. The researchers used a quantitative research design and multiple regression to find out the relationship between the dependent and independent variables. The findings of the study answer the purpose of this paper. It has been found that the relationship between rural-urban migration and the total agricultural output of the Philippines has a negative relationship. Other results showed that the number of people employed in agriculture and average agricultural wage have a positive effect on the country’s total agricultural output while inflation rate has a negative effect. Creating more opportunities for people living in rural areas and strengthening the institutional and governance in the agricultural sector can not only lessen the internal migration but also improve the country’s economy.