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Ni Made Renny A.R
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Medicine & Pharmacology

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SEORANG PENDERITA HEMOFILIA RINGAN DENGAN PERDARAHAN MASIF Renny A.R, Ni Made; Suega, Ketut
journal of internal medicine Vol. 7, No. 2 Mei 2006
Publisher : journal of internal medicine

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Abstract

Haemophilia A is the most common of the hereditary clotting factor deficiencies, which have defect of absence or lowlevel factor VIII in the plasma. It is a X-linked recessive inheritance disease, with incidence approximately 1 per 10.000 malebirth. In the middle of the year 2001,it were reported 314 cases in Indonesia. The clinical features of the bleeding may be shownmany various severity, and classified into mild, moderate and severe disease. The clinical severity of the disease correlates withthe extent of the factor VIII deficiencies. Diagnostic confirm by specific clinical features, there is a history of the bleeding in thefamily, and laboratorium examination to measure the factor VIII level in the plasma. We reported a case, male, 46 years old,Balinese, reffered from private hospital with complaining profuse bloody vomiting and blackish stool and has been done bloodtransfusion for 15 bags, with history of haemophilia confirmed. The history of bleeding before classified patients into a milddisease, but in the present the patient suffered from chronic liver disease and erosive gastritis, that can lead patients has moreprofuse bleeding. A good respons shown by giving the transfusion of the cryopresipitate and packed red cell.
Co-Authors Ketut Suega