Cane Lukisari
Ilmu Penyakit Mulut Fakultas Kedokteran Gigi Universitas Airlangga Surabaya, Indonesia

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Penatalaksanaan kandidiasis oral disebabkan Candida tropicalis pada anak dengan gangguan sistemik Cane Lukisari; Dwi Setyaningtyas; Mintarsih Djamhari
Journal of Dentomaxillofacial Science Vol. 9 No. 2 (2010): Formerly Jurnal Dentofasial ISSN 1412-8926
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/jdmfs.v9i2.236

Abstract

Oral candidiasis is an oral mucosal infection caused by Candida albicans (CA) ornon-Candida albicans Candida (NCAC). C. tropicalis (CT) is most virulent NCACbecause it has the most adherence ability to epithelial cells in vitro as well as mediumlevel proteinase secretion. In addition, CT is the second most common colony found inhuman. Although incidence rate of oral infection was low, this species has virulencepotency, lately reported as the mayor cause of candidemia in immunocompromisedpatients. This paper reports and discusses oral candidiasis due to CT in a child whosuffered anemia with clinical sign of malnutrition. Oral nystatin suspension is therapyof choice because of patient well response, and in vitro studies reported lack ofresponse of fluconazole to candidemia due to C.tropicalis. However, nystatin oralsuspension, should be synchronized with hygiene optimalization of elimination ofpredisposition factors, and supportive therapy would provide a good prognosis.
Penatalaksanaan infeksi Candida tropicalis pada penderita median rhomboid glossitis The management of infection of Candida tropicalis at median rhomboid glossitis patient Cane Lukisari; Kus Harijanti
Journal of Dentomaxillofacial Science Vol. 10 No. 1 (2011): Formerly Jurnal Dentofasial ISSN 1412-8926
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/jdmfs.v10i1.246

Abstract

Oral candidiasis is oral mucosal infectious caused by Candida albicans or non-candida albicans candida (NCAC).Each Candida species infection has same clinical manifestation, the different only in invasive nature and antifungiresponse. C.tropicalis is most virulence NCAC because the most adherence ability to epithelial cells in vitro as wellas medium level proteinase secretion. In addition, C.topicalis is the second most common colony on human. A studyreported of C.tropicalis as causa of 16% hospitalized oral candidiasis, anti fungal drugs and systemic antibioticwas known as trigger factors. This paper report and discuss oral candidiasis due to C.tropicalis in patient, adultmale, with median rhomboid glossitis. The patient also used broad spectrum antibiotic and topical corticosteroidwith imprecise dose. The management of this case was terminated antibiotic and corticosteroid, oral hygieneoptimalization and was given 0.25% chlorhexidine gluconate. However, oral hygiene optimalization, predispositionfactors elimination, and, precise therapy would give a good prognosis.