This study aims to describe the science process skills of students on each indicator and to find out the average percentage of students who have a science process skill level category (high, medium, and low) chemical bonding material with the POGIL learning model. This research uses pre-experimental research with the one group pretest posttest research desaign. The data collection techniques used were observation and assessment tests. The data analysis technique used paired T-Test (SPSS version 16) and N-gain Score. The results showed that the data were normally distributed, namely the Sig.> 0.05. Paired Sample T-Test obtained Sig. (2-tailed) of 0.00, which means that the test is <0.05. So it can be concluded that the POGIL learning model has a significant effect on the science process skills of students. The science process skills of the five indicators, the classification indicator has the highest average posttest score percentage of 96.21% and the observing indicator has the lowest average posttest score percentage of 71.21%. Science process skills have increased from the average results of the pretest and posttest values, namely from 65.76% to 88.41%. The improvement of science process skills is in the moderate category with the N-gain Score index of 0.67.