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Masahiro Yasuda
Graduate School of Bioresources, Mie University, Japan
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology

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ULTRASTRUCTURAL FEATURE OF KOI HERPESVIRUS (KHV) INFECTED CULTURED KOI FIN (KF-1) CELLS Ketut Mahardika; Masahiro Yasuda
Indonesian Aquaculture Journal Vol 6, No 2 (2011): (December 2011)
Publisher : Center for Fisheries Research, Agency for Marine and Fisheries Research and Human Resource

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (585.21 KB) | DOI: 10.15578/iaj.6.2.2011.165-171

Abstract

Koi herpesvirus (KHV), may cause significant morbidity and mortality in common carp (Cyprinus carpio). In the present study, an electron microscopic (EM) was performed on KHV-infected cultured koi fin (KF-1) to document the ultrastructure of the lesions. Viral particles were firstly evident in the nucleus. These viral particles observed as immature capsids and nucleocapsids. Many non-enveloped nucleocapsids have moved from the nucleus into the cell cytoplasm. The formation of subviral particles and virions, which comprised, in turn, an electron dense core, capsids with a hexagonal outline, the tegument was evident in the cytoplasm. And then, the virions with the enveloped tegument budded through the intracytoplasmic membrane. Based on EM results, the definitive pathological change was similar as those in the Family Herpesviridae.
Co-Authors Ketut Mahardika