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CHINAMI KITAMURA
FUKUYAMA UNIVERSITY
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

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Rasio Senyawa Enansiomer sesamin di dalam kulit batang Pentaspadon motleyi (Anacardiaceae) CHINAMI KITAMURA; PARTOMUAN SIMANJUNTAK; KAZUYOSHI KAWAZOE; SHOJI MAEHARA; KOZUYOSHI OHASHI; HIROTAKA SHIBUYA
JURNAL ILMU KEFARMASIAN INDONESIA Vol 9 No 2 (2011): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

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Abstract

The barks of Pentaspadon motleyi Hook. f. (Anacardiaceae) were collected from the Poso district in Central Sulawesi, Indonesia, in 1992 which it has been used traditionally as a remedy for malaria and tuberculosis in the local area. It was found that a mixture of (+)-sesamin (1) and (-)-sesamin (2) in a ratio of 100:86 were present together with lupeol in the bark of Pentaspadon motleyi. This was the first evidence of sesamin being isolated in almost equivalent amounts of (+)- and (-)-forms from a single plant species, and indicates that the biosynthetic pathway of sesamin in the plant is not enantioselective or fuzzy.
Co-Authors HIROTAKA SHIBUYA KAZUYOSHI KAWAZOE KOZUYOSHI OHASHI PARTOMUAN SIMANJUNTAK SHOJI MAEHARA