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ENJANG RUSNAWAN
UNIVERSITAS PANCASILA
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

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Journal : Jurnal Ilmu Kefarmasian Indonesia

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Sintesis dan Uji Antioksidan Senyawa 1,5-bis(3’-etoksi-4’-hidroksifenil)-1,4-pentadien-3-on (EHP) ESTI MUMPUNI; ENJANG RUSNAWAN; EVI SULASTRI; INDRIANA PERMATASARI
JURNAL ILMU KEFARMASIAN INDONESIA Vol 8 No 2 (2010): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

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Abstract

Synthesis of 1,5-bis(3’-etoxy-4’-hydroxyphenyI)-1,4-pentadiene-3-on (EHP) by aldol condensation method from ethyl Vanilin and acetone, using hydrochloride acid as a catalyst, has been conducted. Identification of the EHP compound was done through interpretation of UV-Vis, FT-IR, GC-MS and NMR data, The antioxidant activity of EHP (IC50 8.66 µg/mL) is higher than curcumin (IC50 11.44 µg/mL) as demonstrated by the DPPH method.
Co-Authors Esti Mumpuni EVI SULASTRI INDRIANA PERMATASARI