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All Journal Jurnal Ilmu Kefarmasian Indonesia
PUSPA D.N. LOTULUNG
LEMBAGA ILMU PENGETAHUAN INDONESIA
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

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Aktivitas Antioksidan Senyawa Flavonoid Terprenilasi dari Ekstrak Diklorometana Daun Artocarpus communis PUSPA D.N. LOTULUNG; SOFA FAJRIAH; EUIS FILAILA
JURNAL ILMU KEFARMASIAN INDONESIA Vol 9 No 2 (2011): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

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Abstract

This research investigated the antioxidant activity of prenylated flavonoid compound from the ichloromethane extract of Artocarpus communis leaves on 1,1-diphenyl-2-picryl hydrazyl free radicals scavenging assay. The dichoromethane extract of Artocarpus communis leaves was fractionated by column chromatography techniques on silica gel, and each fraction was assayed for its activity. The active compound, 1-(2,4-dihydroxyphenyl)-3-[8-hydroxy-2-methyl-2-(4-methyl-3-pentenyl)-2H-1-benzopyran-5-yl] 1-propanone, showed moderate antioxidant activity with IC50 54.6 μg mL-1.
Co-Authors EUIS FILAILA SOFA FAJRIAH