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All Journal Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Sainstech Farma: Jurnal Ilmu Kefarmasian
Shirly Kumala
Fakultas Farmasi, Universitas Pancasila
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Pengeringan Beku Ekstrak Herba Pegagan (Centella asiatica) Yonathan Atmodjo Reubun; Shirly Kumala; Siswa Setyahadi; Partomuan Simanjuntak
SAINSTECH FARMA Vol 13 No 2 (2020): Sainstech Farma: Jurnal Ilmu Kefarmasian
Publisher : FAKULTAS FARMASI, INSTITUT SAINS DAN TEKNOLOGI NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37277/sfj.v13i2.764

Abstract

Herba pegagan atau yang biasa dikenal dengan nama daun kaki kuda (Centella asiatica L.) dipercaya oleh masyarakat luas di Indonesia sebagai salah satu pengobatan pada penyakit hipertensi, diabetes, dan meningkatkan memori ingatan seseorang. Tujuan penelitian ini adalah untuk mendapatkan ekstrak herba pegagan yang lebih stabil dalam penyimpanan dengan metode freeze drying dengan menghilangkan kandungan air dalam suatu bahan atau produk yang telah beku tanpa melalui fase cair terlebih dahulu. Tahap awal pengerjaan diawali dengan ekstraksi herba pegagan secara maserasi menggunakan pelarut etanol 96%. Hasil maserasi ekstrak herba pegagan lalu dipekatkan dengan rotary evaporator hingga didapatkan ekstrak kental setelah itu dilakukan freeze drying guna mendapatkan ekstrak kental yang stabil. Hasil penelitian didapatkan ekstrak kental sejumlah 333,37g dari 1.000g simplisia herba pegagan dengan hasil rendemen ekstrak yaitu 33,33 %. Hasil ekstrak setelah dilakukan freeze drying adalah 123,89 g. Hasil tersebut didapatkan bahwa penggunaan metode freeze drying ekstrak herba pegagan mengalami pengurangan bobot yang ditunjukan pada berat hasil ekstrak yang sudah dilakukan pengujian freeze drying. Setelah itu dilakukan penapisan fitokimia dari ekstrak herba pegagan dan didapatkan ekstrak etanol herba pegagan terdapat senyawa alkaloid, saponin, tanin, fenolik, flavonoid, glikosida, triterpenoid, dan steroid.
Risk factors and costs of household perspectives in hemodialysis patients on Hospital Of Bhayangkara Tk. I. R. Said Sukanto Anggelina Aprilia Pangalila; Prih Sarnianto; Shirly Kumala
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 14, No 1 (2020): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (204.768 KB) | DOI: 10.33533/jpm.v14i1.1315

Abstract

The incidence and prevalence of chronic kidney disease (CKD) patients in Indonesia is increasing every year. In the promotion of health promotion and prevention efforts, data related to risk factors and cost analysis are needed from the perspective of patients and / or families related to CKD treatment that requires replacement therapy for kidney function (Hemodialysis / HD). CKD patients undergo HD therapy generally twice a week, making it a relatively large burden on them. This study aims to determine the risk factors for CKD in hemodialysis patients at Bhayangkara Hospital Tk. I R. Said Sukanto and the impact of the cost of HD therapy from a household perspective. In an observational study with this case control method. Primary data was taken through interviews using a structured questionnaire with 100 HD patients (cases) and 100 patients from other poly (control), cross sectional. Risk factor analysis was carried out by logistic regression (p <0.05) and cost analysis using the accounting method. The results showed that in terms of socio-demography, ages above 40-49 years had a risk of 32.7 times and ≥ 50 years had a risk of 17.9 times having CKD compared to <30 years of age with an education level ≤ SD-SMA at risk 16.9 times affected by CKD from the academy / university group, and the income of Rp. 2,000,000 - Rp. 4,000,000 has a risk of 8.4 times being affected by CKD from income groups> Rp. 6,000,000. In terms of biophysiology, hypertension, diabetes and anemia had a risk of 516 times, 54 times and 272 times the effect of CKD. The habit of consuming Chinese and Western herbs increases the risk of developing CKD up to 10.9 times. The cost of the household perspective issued by the patient includes a meal cost of Rp360,000, transportation costs Rp.320,000 and drugs and multivitamins Rp250,000. The potential loss of productivity reaches Rp1,241,904 per patient per month.
Co-Authors Anggelina Aprilia Pangalila Partomuan Simanjuntak Prih Sarnianto Siswa Setyahadi Yonathan Atmodjo Reubun