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All Journal Eduvest - Journal of Universal Studies
Farahdina Farahdina
Brawijaya University
Aerospace Engineering Computer Science & IT Health Professions Neuroscience Social Sciences

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Baroreflex Activation Therapy (BAT) Effectiveness Among Heart Failure Patients: A Systematic Review and Meta-Analysis Farahdina Farahdina; Muhammad Ilham Hernawan; Wiryantari Akhdani Pratiwi; Hapsary Puteri Widodo; Vatine Adila
Eduvest - Journal of Universal Studies Vol. 1 No. 8 (2021): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (352.258 KB) | DOI: 10.59188/eduvest.v1i8.142

Abstract

Heart failure is promoted by the imbalance of sympathovagal, which increased sympathetic and decreased parasympathetic activity. BAT, an electrical stimulation technology, cause the baroreflex to be activated and balances the sympathovagal. Systematic review and meta-analysis were conducted, including published reports about the effectiveness of BAT in heart failure patients from PubMed, Embase, Cochrane, and Google Scholar to calculate the pooled standard mean difference and 95% confidence interval (95% CI) using either random or fixed effect model. Our search strategy identified 161 possible studies. Thirteen studies have been included as a full-text review. We excluded seven of these papers due to review, and our analysis has included six papers. Our combined analysis has shown that BAT is associated with an improvement in NYHA class compared to control (0.19[95%CI: 0.11-0.31], p = 0.000). Our pooled analysis also found that BAT, compared to control, was associated with 6-MHWD improvement, (-136.25[95%CI: -181.34 - -91.17], p = 0.000). Our pooled analysis also found that BAT, compared to control, was associated with HF hospitalization (-6.38[95%CI: -8.46 - -4.30], p = 0.000). BAT has a significant effect on improving NYHA Class, 6-minute hall walk distance, and decreasing HF patient's hospitalization days. Meanwhile, there is an insignificancy on LVEF and QoL improvement in HF patients. Future studies are still needed.
Late Onset Acquired Prothrombin Complex Deficiency (APCD) in a 27 Days Old Infant: a Rare Case Report Farahdina Farahdina; Ima Sri Wahyuni
Eduvest - Journal of Universal Studies Vol. 1 No. 9 (2021): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1607.438 KB) | DOI: 10.59188/eduvest.v1i9.203

Abstract

Acquired prothrombin complex deficiency (APCD) is a disease that occurs due to a deficiency in the coagulation factors that make up the prothrombin complex (II, VII, IX, and X), which are highly dependent on the presence of vitamin K in carrying out their functions. This study uses a qualitative method with the type of case report. The sampling technique used in this study the author uses the Random Sampling technique or by using the Slovin formula in Husein Umar. Where each population has the same opportunity to be selected as a sample in this study. Based on the analysis and discussion, it can be concluded that APCD is a disease with a high mortality rate, and those who survive are also threatened with disability for the rest of their lives. So that early detection and holistic treatment need to be done to prevent death and disability.
Co-Authors Hapsary Puteri Widodo Ima Sri Wahyuni Muhammad Ilham Hernawan Vatine Adila Wiryantari Akhdani Pratiwi