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All Journal Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan
Yuliati Yuliati
Departemen Mikrobiologi FKIK UIN Syarif Hidayatullah Jakarta
Health Professions Medicine & Pharmacology

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UJI EFEKTIVITAS LARUTAN MADU SEBAGAI ANTIBAKTERI TERHADAP PERTUMBUHAN Staphylococcus aureus DAN Pseudomonas aeruginosae DENGAN METODE DISK DIFFUSION Yuliati Yuliati
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 11, No 1 (2017): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (260.115 KB) | DOI: 10.33533/jpm.v11i1.206

Abstract

Honey is one of the traditional medicine that can be used in the community for wound treatment since centuries ago. Honey has an antibacterial effect, due to its high osmolarity , hydrogen peroxide content, low pH and low activity. The pH of honey is acidic (ranges about 3.2-4.5), inhibits the metabolism of Gram negative and positive bacteria, in consequence would be bacterial metabolism inhibition. This condition would lead to bacterial lysis. Honey can be used as wound treatment, controls blood sugar in diabetes patient`s, antioxidants, prevents inflammation outer layer surrounding the mouth of the laser beam treatment of cancer patients, treats gastrointestinal inflammation, as well as the material beauty products, hair and skin. This study was conducted to determine the comparative effectiveness of honey solution on the growth of Staphylococcus aureus and Pseudomonas aeruginosae with various concentrations of 105 ppm, 106 ppm , 5x106 ppm , 107 ppm , and 108 ppm by well diffusion method. According to the MIC result on S .aureus, its is included in weak category, with an average diameter 6.5 mm , 10.5 mm, 12 mm, and 14.7 mm on 106 ppm, 5x106 ppm, 107 ppm, and 108 ppm, respectively. Based on the MIC result on Pseudomonas aeruginosae, it also included in weak category, with an average diameter 6 mm , 8.5 um , 9.5 mm, 10.5 mm on 106 ppm, 5x106 ppm on 106 ppm, 5x106 ppm, 107 ppm, and 108 ppm, respectively. This study concluded that antibacterial from honey solution is more effective against Staphylococcus aureus than Pseudomonas aeruginosae, although there are no significantly difference.
UJI EFEKTIVITAS EKSTRAK KUNYIT SEBAGAI ANTIBAKTERI DALAM PERTUMBUHAN Bacillus sp dan Shigella dysentriae SECARA IN VITRO Yuliati Yuliati
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 10, No 1 (2016): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1520.714 KB) | DOI: 10.33533/jpm.v10i1.11

Abstract

Turmeric is a spice plants that acts as an antibacterial, because it contains a variety of compounds including curcumin and essential oil. Essential oils can be used as an antibacterial because it contains hydroxyl and carbonyl functional group which is phenols derivative. Te phenol derivatives will interact with the bacterial cell wall, then absorbed and penetrated into the bacterial cell, causing precipitation and denaturation of proteins, the result will lyse the bacterial cell membrane, while the antibacterial activity of curcuminis by inhibiting bacterial cell proliferation. Turmeric has launched a pharmacological effect, lowering the fat content, asthma , hepatitis , anti- gall , anti- inflammatory , anti- diarrhea , and act as anti-inflammatory or anti-inflammatory. Turmeric has antibacterial properties of curcumin and essential oil that is capable of inhibiting the growth of bacteria that causes diarrhea and Shigelladysenteriae Bacillus sp. Tis study was conducted to determine the effectiveness of turmeric extract on the growth of Bacillus sp and Shigella dysenteriae, with various concentrations of 15%, 30%, 50%, 75%, and 100% by the well diffusion method. Based on theinhibition zone measurement of bacteria Bacillus sp and Shigella dysenteriaethe results were weak category, for the bacteria Bacillus sp with a concentration of 15 % , 30 % , 50 % , 75 % , and 100 % with a diameter of 11 ; 12.3 ; 13 , 3 ; 13.7 ; 14.7 mm, while for the bacteria Shigella dysenteriae with the same concentration has a diameter of 10.3 ; 11.7 ; 12.3 ; 13.3 , and 14.7 mm. Te conclusion of the study is that the antibacterial activity of turmeric extract is more effective against the bacteria Bacillus spthan against bacteria Shigella dysenteriae, although the difference was not signifcant.
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