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All Journal JOPS (Journal Of Pharmacy and Science) JURNAL PHOTON
Rudi Hendra Sy
Program Sarjana Kimia Fakultas Matematika Dan Ilmu Pengetahuan Alam Kampus Binawidya Pekanbaru, 28293. Riau, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health

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Journal : JURNAL PHOTON

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UJI AKTIVITAS TOKSISITAS DARI EKSTRAK TANAMAN MIANA MERAH (Coleus hybridus) MENGGUNAKAN METODE BSLT ( Brine Shrimp Lethality Test) Dede Indra Syari; Rhida - Aini; Rudi Hendra Sy; Hilwan Yuda Teruna
Sistem Informasi Vol 9 No 1 (2018): Jurnal Photon
Publisher : LPPM Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jp.v9i1.1076

Abstract

Kanker merupakan penyakit yang menakutkan bagi banyk orang. Coleus merupakan satu spesies tanaman dari famili lamiaceae, yang berpotensi sebagai tanaman obat tradisional. Dalam studi berikut ini mempelajari identifikasi aktivitas tosisitas tanaman Coleus hybridus dari fraksi ekstrak n-heksan dan faksi ekstrak etilasetat. Aktivitas toksisitas dilakukan dengan metode BSLT. Hasil dari identifikasi toksisitas dari ekstrak fraksi n-heksan dan fraksi ekstrak etilasetat. Ekstrak n-heksan dan ekstrak etil asetat menunjukan bahwa aktivitas toksisitas untuk LC50 n-heksan >1000 ppm dan ekstrak etil asetat >1000ppm. Ekstrak etil asetat menunjukan aktivitas kedua senyawa negatif sebagai toksisitas.
SKRINING FITOKIMIA DAN UJI TOKSISITAS DARI EKSTRAK DAUN MAHANG (Macaranga bancana) Rianti Putri; Rudi Hendra Sy; Hilwan Yuda Teruna
Sistem Informasi Vol 9 No 2 (2019): Jurnal Photon
Publisher : LPPM Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jp.v9i2.1153

Abstract

Macaranga bancana (Euphorbiaceae) known as “mahang” which is wide spread in Indragiri Hulu, Riau Province and also believed to has medicinal properties. This study to evaluate the secondary metabolites contents and toxicity activity from various extracts of M. bancana leaves. Extraction process were done by using maceration method with various solvents, such as n-hexane, dichloromethane, ethyl acetate, methanol, and ethanol. Toxicity analysis was done by Brine Shrimp Lethality Test (BSLT). The results of phytochemical screening showed that M. bancana leaves contain terpenoid, steroid, flavonoid and phenolic. Toxicity analysis showed that n-hexane extracts prossessed the highest level of toxicity followed by dichloromethane, ethyl acetate and methanol extracts with LC50 value of 65; 87; 227; 605 μg/mL, respectively while ethanol extract has not toxic. Therefore, it could be concluded that M. bancana has good toxicity level and could be used as screening for anticancer.
Co-Authors Dede Indra Syari Hilwan Yuda Teruna Retno Puji Lestari Rhida - Aini Rianti Putri