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All Journal JOURNAL LA MEDIHEALTICO
Nnodim Johnkennedy
Department Of Medical Laboratory Science, Faculty Of Health Science, Imo State University, Owerri, Nigeria
Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Perspective of Inflammation and Inflammation Markers Nnodim Johnkennedy; Okafor Chibuzor Mercy
Journal La Medihealtico Vol. 3 No. 1 (2022): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v3i1.620

Abstract

Progression and occurrence of coronary heart disease can be attributed in part to the presence of inflammation. As a result of our understanding of inflammation's molecular underpinnings, we have identified markers that may also serve as new treatment targets for atherosclerosis. Individuals with and without a history of cardiovascular disease can benefit from monitoring their C-reactive protein (CRP) levels (CVD). The anti-inflammatory characteristics of statins have lately been explored, and they have been shown to significantly lower cardiovascular morbidity and death. C-reactive protein, adiponectin, CD40 ligand, and lipoprotein-associated phospholipase A were the focus of this review, which also looked at statins' effect on these biomarkers and their potential link to cardiovascular events, all of which are thought to be involved in the inflammatory process that leads to atherothrombosis and other cardiovascular diseases.
Evaluation of Pattern of Lipid Profile of Subjects With Different Abo Groups in Madonna University Elele Rivers State Nigeria Nnodim Johnkennedy; Francis Ukpevie Goody
Journal La Medihealtico Vol. 3 No. 2 (2022): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v3i2.621

Abstract

This study looked into how the lipid profiles of people with various ABO blood groups varied. 50 healthy patients with varied ABO blood groups were studied, including 12 A, 12 B, and 10 AB and 16 O blood groups, all of whom appeared to be in good condition and appeared to be asymptomatic. Men and women between the ages of 15 and 25 years old provided informed consent and met the inclusion criteria. Colorimetric measurements of serum lipid profiles were performed on blood samples collected in accordance with routine operating protocols. The results were expressed as MeanSD, and the means of the groups were compared using an analysis of variance (ANOVA). Values with p0.05 were considered significant, whereas those with p>0.05 were not. Averages for TCH and TG in group A were 4.21 and 0.99 millimol/L, respectively. HDL and LDL were both 1.71 and 0.07 millimol/L higher in this group. TCH was 4.2 0.48 mmol/L, TG was 0.74 0.35 mmol/L, HDL was 1.6 0.62 mmol/L, and LDL was 2.26 0.45 mmol/L on average in group B. TCH (4.3 0.88 mmol/L), TG (0.96 0.49 mmol/L), HDL (1.8 0.52 mmol/L) and LDL (1.94 0.81 mmol/L) were found in the group AB patients. When the TCH, TG, HDL, and LDL mean values of the various ABO blood groups were examined, there was no significant difference (p>0.05). This study's findings suggest that blood type has no effect on the serum lipid profile of healthy persons.
Perspective of delayed Hypersensitivity: A review Nnodim Johnkennedy; Njoku-Obi Treasure; Bako Hauwa
Journal La Medihealtico Vol. 3 No. 2 (2022): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v3i2.623

Abstract

T cells enter tissues and are activated by antigen-presenting cells to produce cytokines that cause inflammation in the local area. In allergic contact dermatitis, drug eruptions, asthma, and autoimmune disorders, CD8+ T lymphocytes mediate DTH reactions. As an example of this type IV hypersensitivity, chronic DTH reactions, contact hypersensitivity, and hypersensitivity pneumonitis are all examples. Infiltration of an antigen-exposed region by Th1 cells and macrophages, which inflict tissue damage, is the primary cause of the delayed onset of symptoms. It has thus been outlined that this delayed hypersensitivity reaction.
Co-Authors Bako Hauwa Francis Ukpevie Goody Njoku-Obi Treasure Okafor Chibuzor Mercy