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ASAS-ASAS UTAMA HUKUM KONTRAK DALAM KONTRAK DAGANG INTERNASIONAL: SEBUAH TINJAUAN HUKUM Simanjuntak, Ricardo
Jurnal Hukum Bisnis Vol. 4 No. 1 (2015)
Publisher : jurnalhukumbisnis.com

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Asas-Asas Utama Hukum Kontrak dalam Kontrak Dagang Internasional: sebuah Tinjauan Hukum
BERBAGAI SENGKETA HUKUM YANG DAPAT MUNCUL DARI KONTRAK ASURANSI SERTA PENYELESAIANNYA Simanjuntak, Ricardo
Jurnal Hukum Bisnis Vol. 4 No. 3 (2015)
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Berbagai Sengketa Hukum yang Dapat Muncul dari Kontrak Asuransi serta Penyelesaiannya
PEMBERIAN HAK KHUSUS BAGI PERUSAHAAN ASURANSI DAN RE-ASURANSI, DALAM PASAL 2 AYAT (5) RUU KEPAILITAN, AKANKAH MEMBUAT PERUSAHAAN KEBAL PAILIT Simanjuntak, Ricardo
Jurnal Hukum Bisnis Vol. 5 No. 1 (2016)
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Pemberian Hak Khusus bagi Perusahaan Asuransi dan Re-Asuransi, dalam Pasal 2 ayat (5) RUU Kepailitan, Akankah membuat Perusahaan Kebal Pailit
RANCANGAN PERUBAHAN UNDANG-UNDANG KEPAILITAN DALAM PERSPEKTIF PENGACARA (KOMENTAR TERHADAP PERUBAHAN UNDANG-UNDANG KEPAILITAN) Simanjuntak, Ricardo
Jurnal Hukum Bisnis Vol. 5 No. 4 (2017)
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Rancangan Perubahan Undang-Undang Kepailitan dalam Perspektif Pengacara (Komentar Terhadap Perubahan Undang-Undang Kepailitan)
RELEVANSI EKSEKUSI PUTUSAN PENGADILAN NIAGA DALAM TRANSAKSI BISNIS INTERNASIONAL Simanjuntak, Ricardo
Jurnal Hukum Bisnis Vol. 8 No. 4 (2020)
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Relevansi Eksekusi Putusan Pengadilan Niaga dalam Transaksi Bisnis Internasional
AKIBAT DAN TINDAKAN-TINDAKAN HUKUM TERHADAP PENCANTUMAN KLAUSULA BAKU DALAM POLIS ASURANSI YANG BERTENTANGAN DENGAN PASAL 18 UNDANG-UNDANG NO. 8/1999 TENTANG PERLINDUNGAN KONSUMEN Simanjuntak, Ricardo
Jurnal Hukum Bisnis Vol. 8 No. 5 (2020)
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Akibat Dan Tindakan-Tindakan Hukum Terhadap Pencantuman Klausula Baku Dalam Polis Asuransi Yang Bertentangan Dengan Pasal 18 Undang-Undang No. 8/1999 Tentang Perlindungan Konsumen
Activity of Karamunting Leaf Extract (Rhodomyrtus tomentosa (Aiton) Hassk) as an Antibiofilm on Klebsiella pneumoniae Sabrina, Tia; Simanjuntak, Ricardo; Rivani, Erizka; Zanaria, Rima; Lusiana, Evi
Jurnal Kesehatan Vol 16 No 2 (2025): Jurnal Kesehatan
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v16i2.4982

Abstract

Klebsiella pneumoniae can cause serious infections. The use of antibiotics is often an option in treating infections, but bacteria can adapt by forming biofilms. Therefore, the search for alternative antibiofilms from natural sources is important. One potential plant is karamunting leaves (Rhodomyrtus tomentosa (aiton) hassk). This study aims to describe the potential of the ethanol extract of karamunting leaf as an antibiofilm against Klebsiella pneumoniae. This study is an in vitro descriptive laboratory test. A thick ethanol extract of karamunting leaves was then prepared in three concentration variations: 62.5µg/mL, 125µg/mL, and 250µg/mL. The positive control used was meropenem, and the negative control used was DMSO. The parameter measured for the inhibition and eradication test was biofilm thickness, which was read using a 590nm Microplate reader. In this study, the percentage of inhibition in the three concentrations was 90.65% at a concentration of 250 µg/ml, 86.69% at a concentration of 125µg/ml, and 87.22% at a concentration of 62.5µg/ml. During the eradication test, the percentages obtained were -10.67% at a concentration of 250µg/ml, 3.58% at a concentration of 125µg/ml, and 68.23% at a concentration of 62.5µg/ml. The ethanolic extract of karamunting leaves demonstrates good biofilm inhibitory activity against Klebsiella pneumonia at all tested concentrations. At a concentration of 62.5µg/ml, the extract exhibits good biofilm eradication activity, while at 125µg/ml and in the positive control, it shows poor activity. Interestingly, at a concentration of 250µg/ml, the extract acts as a biofilm promoter, enhancing biofilm formation.