Article Per Year (5 Year)
p-Index From 2020 - 2025
0
P-Index
This Author published in this journals
All Journal Jurnal Kimia (Journal of Chemistry)
iurlina Siregar
Unknown Affiliation
Chemistry

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
PERTUMBUHAN Streptococcus mutans PADA BIOAKTIVITAS EKSTRAK RIMPANG LENGKUAS SECARA in vitro DAN PEMANFAATANNYA SEBAGAI ZAT AKTIF PADA PASTA GIGI iurlina Siregar; Ferdinand Saras Dhiksawan; Anna Farida
Jurnal Kimia (Journal of Chemistry) Vol. 5, No. 1 Januari 2011
Publisher : Program Studi Kimia, FMIPA, Universitas Udayana (Program of Study in Chemistry, Faculty of Mathematics and Natural Sciences, Udayana University), Bali, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (342.542 KB)

Abstract

The study aims to (i) isolate white galangal (Alpinia galanga) and red (Alpinia purpuruta) rhizome extract compound, (ii) examine its bioactivity against Staphylococcus mutans, and (iii) investigate its usage as an active substance in tooth paste in the laboratory. The result of the study indicates that the extract of n-hexane of red galangal has a higher bioactivity effect against Staphylococcus aureus compared to the white one. The examination of the experimental tooth paste with an addition of 1 % active substance (extract of n-hexane, namely D and J fractions) indicates that the diameter of resistance against Staphylococcus aureus formed by D fraction is higher (15.5 mm) than the positive control (15 mm). Meanwhile, an addition of active substance of 1.5 % D and J fractions indicates a higher diameter of resistance (16.2 mm and 14.7 mm) compared to positive control.. IR and GC-MS analysis indicates that the most dominant compound existing in D fraction is 2-metil -1-(o-tolil)pentanol, while the most dominant compound in the J fraction is 2--ethyl-5-methyl benzoic acid.
Co-Authors Anna Farida Ferdinand Saras Dhiksawan