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All Journal Althea Medical Journal
Truly D. Sitorus
Department of Pharmacology and Therapy
Medicine & Pharmacology

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Journal : Althea Medical Journal

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Antibiotic Conformity with Culture Results of Hospitalized Pneumonia Patients in Melati Ward at Dr. Hasan Sadikin General Hospital Bandung, Indonesia Rinaldi, Randhi; Supriatna, Yana Akhmad; Sitorus, Truly D.; Sudjana, Primal
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Althea Medical Journal

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Background: Pneumonia is an infection with the highest mortality rate in Indonesian hospitals. According to The American Thoracic Society and The Infectious Diseases Society of America (ATS/IDSA), empirical use of antibiotics is still effective for pneumonia treatment. Inappropriate use of antibiotics would cause negative effects such as prolonged hospitalization, a high cost of treatment, and increased antibiotic-resistant bacteria. The goal of this study was to clarify the empirical use of antibiotic conformity with a bacteria culture. Methods: This study was conducted from August to October 2013 using a descriptive retrospective method based on 116 medical records of pneumonia patients hospitalized in Melati Ward, Dr. Hasan Sadikin General Hospital Bandung during 2011–2012. The type of bacteria, conformity with antibiotics given to patients, and type of antibiotics were analyzed. The conformity of antibiotics was assessed based on the resistance test. If the results were sensitive, they would be put in the conforming group and in the non-conforming group if the results were resistant or intermediate. Data was derived with descriptive statistics, using percentage and frequency distribution, illustrated in tables and figures.Results: Based on culture results and sensitivity of antibiotic empirical therapy given, 55.17% cases were conformed. The most widely used antibiotic group was Third-generation Cephalosporin (60.34%). The most common bacterias were Klebsiella pneumonia (34.5%) and Acinetobacter baumanni (13.8%).Conclusions: Most of the antibiotics given to pneumonia patients are still appropriate with results of the bacteria culture test and resistance test. [AMJ.2016;3(4):504–8] DOI: 10.15850/amj.v3n4.931
Red Ear Fungi (Auricularia Auricula) Infusion Reduce Blood Triglyceride Level in Dyslipidemic Rats Widi, Nareswara Anugrah; Sitorus, Truly D.; Rita, Coriejati
Althea Medical Journal Vol 2, No 2 (2015)
Publisher : Althea Medical Journal

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Background: Dyslipidemia is a risk fastor in atherosclerosis. In the long run, it can cause complications such as coronary artery disease and stroke. Dyslipidemia can be halted by beta glucan, a soluble fiber found in some species of fungi. This study was conducted to find the effect of red ear fungi infusion in reducing blood triglyceride level and the concentration that will give optimal reduction of blood triglyceride level.Methods: This was an analytical study using experimental laboratoric method. The study conducted in 25 male Wistar rats sorted in 5 groups during the period of September to October 2012 in Pharmacology Laboratory of General Hospital Hasan Sadikin, Bandung.Results: The result showed that mean difference of all three treatment group, which is group 3, group 4, and group 5 (87.08, 90.40, and 82.70 respectively) showed significancy compared to the positive control (group 2). Out of the three group, group 4 with 36% infusion concentration has the lowest mean difference from all of the treatment groups.Conclusions: Red ear fungi infusion reduce blood triglyceride level and infusion with 36% concentration was the optimal concentration in reducing blood triglyceride level. A further study can be done to find concentration range in which the infusion reduce blood triglyceride level optimally.Key words: beta glucan, red ear fungi infusion, triglyceride
Co-Authors Coriejati Rita Nareswara Anugrah Widi, Nareswara Anugrah Primal Sudjana Rinaldi, Randhi Yana Akhmad Supriatna, Yana Akhmad