Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal Jurnal Anestesiologi Indonesia Medica Hospitalia
Danu Soesilowati
Bagian Anestesiologi dan Terapi Intensif RSUP Dr. Kariadi
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Faktor Komorbid Yang Berpengaruh Terhadap Luaran Penyakit Covid 19 Di Intensive Care Unit RSUP Dr Kariadi Semarang Harahap, Sofyan; Mulyono, Harry; Soesilowati, Danu
Medica Hospitalia : Journal of Clinical Medicine Vol. 8 No. 3 (2021): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (302.182 KB) | DOI: 10.36408/mhjcm.v8i3.606

Abstract

BACKGROUND : Sars-Cov2 has become a pandemic and caused health problems. Several factors that worsen the condition of Covid-19 include age, previous comorbid diseases, secondary infections, and increased inflammatory indicators. There are many studies on the factors that influence the outcome of Covid-19, but the results are inconsistent. Thus, specific research in certain areas is needed so that it can be used in local management. OBJECTIVE: This study aims to determine the factors that influence the outcome of Covid-19 in the intensive care unit of the Dr. Kariadi Hospital METHOD : This study analyzed covid 19 patients in the ICU of Dr Kariadi Hospital for the period March-September 2020 with a retrospective method and purposive sampling. The hypothesis test used is adjusted to the measurement scale of each variable. The initial analysis was univariate using chi-square, fisher, t-test, and mann-whitney. RESULT : From this study, it was found that the factors that influence the covid-19 outcome in a bivariate include a history of heart disease (p = 0.037), temperature (p = 0.012), respiratory rate (p = 0.030), oxygen saturation (p = 0.021), platelets ( p = 0.015), ureum (p = 0.034), PO2 (p = 0.002), oxygen fraction (FiO2) (p = 0.034), AaDO2 (p = 0.004), and PFR (p = 0.001). CONCLUSION : History of heart disease, temperature, respiratory rate, oxygen saturation, platelets, urea, PO2, required oxygen fraction (FiO2), AaDO2, and PFR were predictors of Covid-19 mortality which were both theoretically and statistically significant.,independent or simultaneously
Comparison Of Inferior Vena Cava Distensibility Index and Pulse Pressure Variation as Predictors Of Fluid Responsiveness in Sepsis Patients at ICU Evandrian, Difa Aulia; Soesilowati, Danu; Rakhmajati, Pradana Bayu
JAI (Jurnal Anestesiologi Indonesia) Publication In-Press
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.69705

Abstract

Background : Sepsis is a major global health challenge with an estimated 49 million incident cases and 11 million deaths each year, which requires appropriate fluid management to improve patient prognosis. This study aims to compare the effectiveness of Inferior Vena Cava Distensibility Index (IVC-DI) and Pulse Pressure Variation (PPV) as predictors of fluid responsiveness in sepsis patients in the ICU.Methods : This study used an experimental design with a sample of 36 sepsis patients selected through consecutive sampling. Fluid administration of 500 ml RL was carried out for 15 minutes, followed by measurement of IVC-DI and PPV, and evaluation of an increase in Stroke Volume (SV) > 15% as an indicator of fluid responsiveness.Results : The study showed that PPV had a sensitivity of 93% and specificity of 90%, with a positive predictive value of 87.5% and a negative predictive value of 95%. The overall accuracy of PPV was 91.6%. PPV showed a very strong correlation with SV increase > 15% (r = 0.832, p < 0.001). On the other hand, IVC-DI had a sensitivity of 80% and specificity of 71%, with a positive predictive value of 66% and a negative predictive value of 83%. The overall accuracy of the IVC-DI was 75%. The IVC-DI showed moderate correlation with SV increase >15% (r = 0.507, p = 0.002). Inter-observer agreement in IVC-DI measurements also showed excellent results with a Kappa value of 1.00, indicating perfect agreement. From the results of this study, PPV proved to be more accurate in predicting fluid responsiveness compared to IVC-DI in sepsis patients in the ICU. These two methods, although equally useful, showed different levels of effectiveness in this clinical context.Conclusion : This study makes an important contribution to the selection of method to assess fluid responsiveness in sepsis patients, which can assist in better clinical decision-making and improve patient care outcomes in the ICU.Keywords : Sepsis, Fluid Responsiveness, Pulse Pressure Variation, Inferior Vena Cava Distensibility Index, Intensive Care Unit.
Co-Authors Evandrian, Difa Aulia Mulyono, Harry Rakhmajati, Pradana Bayu Sofyan Harahap