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EFFECT OF SAPPAN WOOD (Caesalpinia sappan L) EXTRACT ON BLOOD GLUCOSE LEVEL IN WHITE RATS Saefudin, Saefudin; Pasaribu, Gunawan; Sofnie, Sofnie; Basri, Efrida
Indonesian Journal of Forestry Research Vol 1, No 2 (2014): Indonesian Journal of Forestry Research
Publisher : Secretariat of Forestry Research and Development Agency

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20886/ijfr.2014.1.2.109-115

Abstract

Sappan wood or kayu secang (Caesalpinia sappan L.) was reported of having medicinal properties,  such as  natural antioxidant, relieve vomiting of blood, and mix of ingredients for malaria drugs.  The research was conducted to study the influence of ethanol extract from sappan wood on blood glucose level of white rats. The study of the blood glucose level in rats was carried out by using glucose tolerance method. It was measured by Refloluxs (Accutrend GC) with Chloropropamide 50 mg/200 g BW (Body weight) as positive control. The ethanol extracts were used in various concentrations 10, 20, 30, 40 and 50 mg/200 g BW per-oral and was observed every  hour,  beginning one hour before to 7 hours after the extract being administered. The results showed that treatment of ethanol extract of sappan wood by administer doses gave remarkable effect on the blood glucose level in white rat. It reduced the glucose level in the blood compared to the negative and positive control. Treatment of dose 30 mg/200 g BW gave similar effect to positive controls, while a dose of 50 mg/200 g BW gave lower blood glucose level (93 mg/dl) than the positive controls.
EFFECT OF SAPPAN WOOD (Caesalpinnia sappan L) EXTRACT ON BLOOD GLUCOSE LEVEL IN WHITE RATS Saefudin, Saefudin; Pasaribu, Gunawan Trisandi; Sofnie, Sofnie; Basri, Efrida
Indonesian Journal of Forestry Research Vol 1, No 2 (2014): Indonesian Journal of Forestry Research
Publisher : Secretariat of Forestry Research and Development Agency

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (193.078 KB) | DOI: 10.20886/ijfr.2014.1.2.%p

Abstract

Sappan wood or kayu secang (Caesalpinia sappan L.) was reported of having medicinal uses,  such as  for natural antioxidant, relieve vomiting of blood, and ingredients mix for malaria drugs.  The research was conducted to study the influence of ethanol extract from sappan wood on blood glucose level of white rats. The blood glucose level in rats was carried out by using glucose tolerance method. It was measured by Reflolux S (Accutrend GC) and Chloropropamide 50 mg/200 g BW (Body Weight) as positive control. The ethanol extracts were used in various concentration 10, 20, 30, 40 and 50 mg/200 g BW per-oral and observed every an hour and beginning one hour before to 7 hours after the extract being administered. The results showed that the administered dose 30 mg/200 g BW of the ethanol extracts equal the positive control. Statistical analysis gave significant differential (P<0,05) in 2 and 3 hour after treatment.
EFFECT OF SAPPAN WOOD (Caesalpinnia sappan L) EXTRACT ON BLOOD GLUCOSE LEVEL IN WHITE RATS Saefudin, Saefudin; Pasaribu, Gunawan Trisandi; Sofnie, Sofnie; Basri, Efrida
Indonesian Journal of Forestry Research Vol. 1 No. 2 (2014): Indonesian Journal of Forestry Research
Publisher : Association of Indonesian Forestry and Environment Researchers and Technicians

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59465/ijfr.2014.1.2.109-115

Abstract

Sappan wood or kayu secang (Caesalpinia sappan L.) was reported of having medicinal properties, such as natural antioxidant, relieve vomiting of blood, and mix of ingredients for malaria drugs. The research was conducted to study the influence of ethanol extract from sappan wood on blood glucose level of white rats. The study of the blood glucose level in rats was carried out by using glucose tolerance method. It was measured by Refloluxs (Accutrend GC) with Chloropropamide 50 mg/200 g BW (Body weight) as positive control. The ethanol extracts were used in various concentrations 10, 20, 30, 40 and 50 mg/200 g BW per-oral and was observed every hour, beginning one hour before to 7 hours after the extract being administered. The results showed that treatment of ethanol extract of sappan wood by administer doses gave remarkable effect on the blood glucose level in white rat. It reduced the glucose level in the blood compared to the negative and positive control. Treatment of dose 30 mg/200 g BW gave similar effect to positive controls, while a dose of 50 mg/200 g BW gave lower blood glucose level (93 mg/dl) than the positive controls.
Co-Authors Efrida Basri Gunawan Pasaribu Gunawan Trisandi Pasaribu, Gunawan Trisandi Saefudin Saefudin