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All Journal International Journal of Cardiovascular Practice
Morteza Safi
Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran
Medicine & Pharmacology

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Strategy to manage T-Wave Oversensing in a Biventricular ICD Mohammad Ali Akbarzadeh; Mohammad Hassan Namazi; Morteza Safi; Mehdi Sheibani
International Journal of Cardiovascular Practice Vol. 2 No. 2 (2017)
Publisher : Publisher: Shahid Beheshti University of Medical Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21859/ijcp-020205

Abstract

T-wave oversensing is a relatively prevalent cause of intracardiac signals oversensing in patients with Implantable Cardioverter Defibrillator (ICD). Some of these oversensings are typically corrected with device reprogramming. If reprogramming fails to resolve the issue, invasive options such as repositioning the implanted lead may be necessary. We present a patient with dilated cardiomyopathy and intermittent T wave oversensing by a cardiac resynchronization therapy (CRT) that was managed by altering V-V timing.
Correlation of platelet indices with TIMI frame count in patients undergoing primary PCI due to ST-segment elevation myocardial infarction Ayoub Salehi; Mohammad Hasan Namazi; Morteza Safi; Hossein Vakili; Habibollah Saadat; Saeed Alipour Parsa; Mohammad Ali Akbarzadeh; Ameneh Moshtaghi; Isa Khaheshi
International Journal of Cardiovascular Practice Vol. 4 No. 3 (2019)
Publisher : Publisher: Shahid Beheshti University of Medical Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29252/ijcp-26632

Abstract

Introduction: Given the fundamental role of platelet indices in the development of atherosclerotic plaque, these indices may play a predictive role for the occurrence of disturbed coronary reperfusion. The present study evaluated the relationship between platelet indices and coronary reperfusion status based on TIMI frame count.Methods: This cross-sectional study was conducted on 98 consecutive patients with STEMI who were candidate for primary PCI at Modarres Hospital in Tehran between January 2016 and January 2018. Venous samples were extracted from all patients before primary PCI. To assess the condition of coronary reperfusion after primary PCI, TIMI frame count related to culprit artery in acute myocardial infarction was determined.Results: The TIMI frame count was positively associated with platelet count (r = 0.320, p = 0.001) and more strongly with platelet to lymphocyte ratio (r = 0.375, p < 0.001), but not with other platelet indices such as PDW, MPV, or PLCR. According to the ROC curve analysis, platelet to lymphocyte ratio was introduced as a valuable parameter for differentiating complete from disturbed reperfusion (AUC = 0.735, 95%CI: 0.613 – 0.858, P = 0.001). The best cutoff value for platelet to lymphocyte ratio in predicting disturbed reperfusion was 146.5 yielding a sensitivity of 81.8% and a specificity of 60.5%. However, other platelet indices could not present this predictive role.        Conclusion: From different platelet indices, the platelet to lymphocyte ratio with predictive accuracy and sensitivity predict coronary perfusion impairment based on the increase in TIMI frame count.
Co-Authors Ameneh Moshtaghi Ayoub Salehi Habibollah Saadat Hossein Vakili Isa Khaheshi Mehdi Sheibani Mohammad Ali Akbarzadeh Mohammad Ali Akbarzadeh Mohammad Hasan Namazi Mohammad Hassan Namazi Saeed Alipour Parsa