<![CDATA[Abstrak Pendahuluan :Anemia dijumpai pada sebagian besar penderita Penyakit Ginjal Kronik (PGK) dengan hemodialisis reguler.Berbagai studi invitro invivo menunjukkan pelepasan sitokin proinflamasi ke dalam darah berkontribusi timbulnya anemia.lnterleukin-6 berperan dalam regulasi dan metabolisme besi..Serum ferri1in masih diandalkan menentukan cadangan besi.Metode : Penelitian inimenggunakan metode analitik observasional pendekatan potong lintang yang dilakukan di RSUP H. Adam Malik Medan,maret-april 2016. Sebanyak 35 sampel penderita PGK yang memenuhi kriteria inklusi dan eksklusi.Subjek penelitian diperika darah lengkap, serum feritin dan interleukin 6. Hasil : Subyek 23 laki-laki (65%), 12 perempuan (35%). Dijumpai 24 orang (68.6%} kadar feritin meningkat,dan 11 (31.4%} yang normal. Sedangkan nilai IL-6 >100 pg/ml diperoleh 9 orang (25.7%) dan 10-100 pg/ml adalah 26 orang (74.3%).Pada uji spearman tidak didapat hubungan bermakna interleukin 6 dengan serum feritin (r= 0.028, p = 0.872) .Simpulan : Tidak terdapat hubungan yang signifikan antara interleukin 6 dengan serum feritin pada penderita PGK yang menjalani hemodialisis reguler. Kata kunci : Interleukin 6.feritin,PGK,hemodialisis Abstract Introduction :Anemia is found in most patients with Chronic Kidney Disease(CKD) undergoing regular hemodialysis.lnvitro invivo studies indicated that the release of cytokines in the blood contribute to the onset of anemia.Interleukin 6 plays a role in iron regulation .Ferritin serum is relied to show iron storage in CKD. Method :This study is using analytical observation method and cross sectional design that were conducted at HAM Hospital in March- April 2016.A total of 35 samples of CKD patients Result : Ferritin levels increased in 24 people {68. 6%) and was normal in 11(31.4%).Whereas IL-6 level obtained in 9 people (25.7%)were >100 pg/dl and in 26 (74.3%} were 10-100 pg/dl. In the spearman test there was no significant corellation IL-6 with ferritin serum (r= 0.028, p = 0.872) . Conclusion :There is no significant correlation between Interleukin 6 with ferritin serum in chronic kidney disease patientsKeywords :Interleukin 6, ferritin, CKD, Hemodialysis]]>
