Article Per Year (5 Year)
p-Index From 2021 - 2026
0.659
P-Index
This Author published in this journals
All Journal Jurnal Anestesiologi Indonesia Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Open Access Indonesian Journal of Medical Reviews
Andy Nugroho
Anesthesiology And Intensive Therapy, Faculty Of Medicine, Sebelas Maret University, Solo
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Public Health

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
PERBEDAAN EFEKTIVITAS GABAPENTIN 600 MG PERORAL DENGAN LIDOKAIN 1.5 MG/KGBB INTRAVENA TERHADAP RESPON HEMODINAMIK PASKA INTUBASI ENDOTRAKEAL Andy Nugroho; Sugeng Budi S; Heni Handayani
JURNAL KEDOKTERAN DAN KESEHATAN Vol 9, No 3 (2022)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/JKK.V9I3.17726

Abstract

Penggunaan laringoskop dan penempatan pipa endotrakeal mempengaruhi respon hemodinamik. Penelitian sebelumnya menunjukkan bahwa lidokain dan gabapentin dapat menurunkan respon hemodinamik setelah intubasi. Tujuan dari penelitian ini adalah untuk menganalisis perbedaan efektivitas pemberian gabapentin oral 600 mg dan lidokain 1,5 mg/kg intravena terhadap respon hemodinamik setelah pemasangan pipa endotrakeal. Randomized control trial single-blind dilakukan di ruang bangsal dan ruang operasi di Rumah Sakit Dr. Moewardi, Surakarta. Para pasien diacak dan dibagi menjadi 2 kelompok: 600 mg gabapentin oral 2 jam sebelum intubasi dan 1,5 mg/kg lidokain intravena 90 detik sebelum intubasi. Tekanan darah dan denyut jantung diukur sebelum induksi, setelah laringoskopi, dan 1, 3, 5, 10 menit setelah intubasi. Uji T dan uji Mann-Whitney dilakukan untuk perbandingan. Perbedaan rerata signifikan secara statistik pada variabel denyut jantung (p = 0,032), tekanan darah sistolik (p = 0,045), dan tekanan darah diastolik (p = 0,004) pada menit pertama. Selain itu, nilai rata-rata lidokain selalu lebih rendah dari gabapentin. Lidokain intravena 15 mg/kg lebih efektif dalam menurunkan respon hemodinamik setelah intubasi endotrakeal dibandingkan dengan gabapentin oral 600 mg.
Comparative Evaluation of Target-Controlled Infusion versus Syringe Pump Bolus for Remifentanil Administration on the Incidence of Apnoea and Bradycardia during General Anaesthesia Induction: A Double-Blind Pilot Randomised Controlled Trial Ardhana Surya Aji; Bambang Novianto Putro; Andy Nugroho
Open Access Indonesian Journal of Medical Reviews Vol. 6 No. 2 (2026): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v6i2.876

Abstract

Remifentanil is widely utilized during general anaesthesia induction to attenuate adverse haemodynamic responses to tracheal intubation. However, its profound analgesic efficacy is inherently linked to dose-dependent adverse effects, primarily opioid-induced respiratory depression (apnoea) and bradycardia. This pilot study evaluates the safety profile of pharmacokinetically guided target-controlled infusion (TCI) compared to conventional syringe pump (SP) bolus administration. A double-blind, pilot randomised controlled trial was conducted involving 36 ASA I–II patients undergoing elective maxillofacial surgery. Patients received a standardized co-induction of propofol (2.0 mg/kg), followed by remifentanil via SP (1 µg/kg over 60 seconds) or TCI (initial effect-site concentration [Ce] of 6 ng/mL for 5 minutes, reduced to 4 ng/mL). Primary outcomes were the incidence of apnoea (>15 seconds) and bradycardia (<50 bpm). Apnoea occurred in 33.3% of the SP group versus 16.7% in the TCI group (RR 2.00; p=0.222). Mean onset of apnoea was 41.0±11.0 seconds (SP) and 31.0±3.6 seconds (TCI) (p=0.085). Bradycardia was observed in 72.2% of the SP cohort and 50.0% in the TCI cohort (RR 1.44; p=0.153). All bradycardic events were transiently managed with 0.5 mg of atropine. In conclusion, in this pilot cohort, remifentanil delivered via TCI did not achieve statistical superiority over SP bolus administration in reducing the incidence of apnoea or bradycardia. Fully powered clinical trials are required to definitively establish any pharmacokinetic safety advantages.
Safe and Effective Perioperative Management in Patients with Atrial Septal Defect and Pulmonary Contusion: A Case Study with Supraclavicular Block RTH Supraptomo; Andy Nugroho; Muhammad Baihaqi Siddik
JAI (Jurnal Anestesiologi Indonesia) Publication In-Press
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.78083

Abstract

Background: Peripheral nerve blocks offer a safer anesthetic alternative in patients with congenital heart disease (CHD) by reducing cardiovascular and pulmonary risks associated with general anesthesia. The supraclavicular brachial plexus block provides effective anesthesia for upper limb surgery with improved hemodynamic stability, reduced complications, and better postoperative analgesia. This case report aims to demonstrate the safety and effectiveness of supraclavicular brachial plexus block as a perioperative anesthetic strategy in a high-risk patient with CHD and pulmonary contusion.Case: A 67-year-old woman with a large secundum atrial septal defect (ASD), severe pulmonary hypertension, right ventricular dysfunction, and bilateral lung contusions on day 10 was scheduled for open reduction internal fixation (ORIF) of a distal radius fracture. Due to high cardiopulmonary risk, regional anesthesia was chosen. An ultrasound- and nerve stimulator-guided supraclavicular block using 20 mL of levobupivacaine 0.375% was performed. The procedure was completed successfully with stable hemodynamics and preserved spontaneous ventilation. Postoperatively, the patient was monitored in a high-care unit (HCU).Discussion: Maintaining hemodynamic stability and avoiding increases in pulmonary vascular resistance (PVR) are critical in acyanotic left-to-right shunt CHD. General anesthesia and mechanical ventilation may disrupt Qp:Qs balance and worsen pulmonary function, especially in pulmonary contusion. Regional anesthesia minimizes these risks while providing adequate surgical conditions.Conclusion: Supraclavicular brachial plexus block is a safe and effective alternative for upper limb surgery in high-risk CHD patients with acyanotic shunt lesions and pulmonary complications.
Co-Authors Ardhana Surya Aji Bambang Novianto Putro Heni Handayani Muhammad Baihaqi Siddik RTH Supraptomo Sugeng Budi S