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All Journal JURNAL ILMIAH KESEHATAN SANDI HUSADA Jurnal Ilmiah Kesehatan Sandi Husada
Natalia Danayati
Universitas Lampung
Health Professions Nursing Public Health

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Pengaruh Irisin pada Pencoklatan Lemak Putih Natalia Danayati
Jurnal Ilmiah Kesehatan Sandi Husada Vol 10 No 2 (2021): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v10i2.611

Abstract

Introduction: Irisin is a new myokine that links physical activity to increased metabolic performance and is associated with the browning of white adipose tissue to brown. Objective: To determine the effect of irisin on the browning of white fat. Methods: Using literature studies from scientific sources by summarizing publications and comparing the results presented. Results: Irisin, which is secreted from muscle, stimulates the expression of uncoupling protein 1 (UCP1) in adipocytes that causes browning of white adipose tissue via p38 mitogen-activated protein kinase (MAPK) and via extracellular-signal-regulated kinase (ERK). Conclusion: Irisin secreted by skeletal muscle will express UPC-1 in adipose tissue which causes white adipose tissue to brown and increase thermogenesis activity.
Pengaruh Irisin pada Pencoklatan Lemak Putih Natalia Danayati
Jurnal Ilmiah Kesehatan Sandi Husada Vol 10 No 2 (2021): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v10i2.611

Abstract

Introduction: Irisin is a new myokine that links physical activity to increased metabolic performance and is associated with the browning of white adipose tissue to brown. Objective: To determine the effect of irisin on the browning of white fat. Methods: Using literature studies from scientific sources by summarizing publications and comparing the results presented. Results: Irisin, which is secreted from muscle, stimulates the expression of uncoupling protein 1 (UCP1) in adipocytes that causes browning of white adipose tissue via p38 mitogen-activated protein kinase (MAPK) and via extracellular-signal-regulated kinase (ERK). Conclusion: Irisin secreted by skeletal muscle will express UPC-1 in adipose tissue which causes white adipose tissue to brown and increase thermogenesis activity.
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