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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Majalah Obat Tradisional Indikator: Jurnal Ilmiah Manajemen & Bisnis Indonesian Journal on Medical Science (IJMS) Jurnal Kesehatan Husada Gemilang
Rini Sulistyawati
Akademi Analis Farmasi dan Makanan Al Islam Yogyakarta
Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Dentistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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PENGARUH PENGEMBANGAN KARIR; KOMPENSASI DAN LINGKUNGAN KERJA TERHADAP KINERJA KARYAWAN CV SUMBER BARU NIAGA Saluy, Ahmad Badawi; Sulistyawati, Rini
Indikator: Jurnal Ilmiah Manajemen dan Bisnis Vol 1, No 3 (2017)
Publisher : Universitas Mercu Buana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22441/indikator.v1i3.2327

Abstract

This research aims to analyze the influence of the employees development; compensation and working environment on performance against partial and simultaneously at CV Sumber Baru Niaga. Research design is a descriptive quantitative research  using a sample of 100 respondents as samples at the same time the population or sample is called saturated sampling. Model test using SPSS version 18.0.0.0. Test validity and reliability using Pearson Product Moment with significance level 0.05 and 0.01 multicollinearity test; with a threshold of tolerance of 0.10; test using the test of normality Kolmogorov-Smirnov. The conclusion that results obtained concludes the employee development and work environment has no significant influence on performance employees; hence the compensation and benefit has a significant influence on performance of employees. Simultaneously employee development; compensation; and work environment have a significant influence on performance of employees.
Formulasi dan Uji Stabilitas Fisik Sediaan Hair Tonic Ekstrak Etanol Daun Pare (Momordica charantia L.) Puspitasari, Adellia; Sulistyawati, Rini
Indonesian Journal on Medical Science Vol 11 No 2 (2024): IJMS 2024
Publisher : Unit Penelitian dan Pengabdian Masyarakat Politeknik Kesehatan Bhakti Mulial

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70050/ijms.v11i2.494

Abstract

Bitter melon (Momordica charantia L.) contains flavonoid, saponin, alkaloid, polifenol, momoridicin, cucurbitacin glycoside and charantin. This study aims to determine the hair tonic formulation of bitter melon leaves extract and evaluate its physical stability. The hair tonic formulation was made bitter melon leaves ethanol extract variation concentration i.e FI 3 gram, FII  6 gram and FIII 9 gram,VCO, menthol, propylene glycol, tween 80, nipagin, nipasol and distilled water. Hair tonic physical stability test was cariied out for 12 days of storage and determined for organoleptic test, homogeneity, pH test and viscocity. Organoleptic test result showed FI, FII, FIII were slightly green, green intense green colour respectively, characteristic odor, and liquid form. The homogeneity test of the 3 formulas showed homogeneous results, the pH test of FI, FII and FIII had pH values of 6, 6 and 7. The viscosity test results obtained values of 12.5 cP, 11 cP and 11.50 cP. Formula II gives the best formula results with physical characteristics of green colour, characteristic odor, homogeneous, pH 6 and viscosity value of 11 cP.
The Hepatoprotective Effect of Moringa oleifera Leaves on Male Wistar Rat Induced Streptozotocin-Nicotinamide Bachri, Moch Saiful; Nurani, Laela Hayu; Edityaningrum, Citra Ariani; Ma'ruf, Muhammad; Sulistyorini, Dwi Agustin; Amelia, Rizki; Hidayati, Sholihatil; Sulistyawati, Rini; Guntarti, Any
Majalah Obat Tradisional Vol 29, No 2 (2024)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.90806

Abstract

Diabetes mellitus is a disease characterized by uncontrolled increases in blood sugar levels, which can cause complications in the liver. Disorder liver disease can be seen from the increasing SGOT, SGPT activity, and the number of necrosis cells in the liver. Moringa leaves contain the flavonoid quercetin with antidiabetic and antioxidant activity. This research aimed to determine the effect of administering the ethyl acetate fraction of Moringa leaves on SGOT activity, SGPT, and liver histopathology in rat induced by streptozotocin and nicotinamide. Moringa leaves macerated with 80% ethanol and fractionated with ethyl acetate were used. The research subjects were 30 rats divided into six groups. The rats were induced with streptozotocin at a dose of 65 mg/kgBW and nicotinamide 100 mg/kgBW for five days, then treated for ten days. Serum SGOT and SGPT activity were measured using a Microlab 300 Semi-Automated at a wavelength of 340 nm. Histopathological observations were carried out when the rats were dislocated, their livers were taken, and then preparations were made using Hematoxylin Eosin (HE) staining. Data were analyzed using the SPSS One Way ANOVA method, followed by the Tukey test with a confidence level of 95%. The results of the study showed that administration of Ethyl Acetate Fraction of Moringa oleifera (EA-MO) could reduce the levels of SGOT, SGPT, and the number of liver necrosis cells in rats induced by streptozotocin and nicotinamide.
PENGARUH PENYULUHAN PENGGUNAAN JAMU KUNYIT ASAM TERHADAP TINGKAT PENGETAHUAN REMAJA DUSUN NGEMPLAK, CATURHARJO, SLEMAN Eka Rahayuningsih, Yuni; Sulistyawati, Rini; Murni Hartini, Windadari
Jurnal Kesehatan Husada Gemilang Vol 8 No 2 (2025): JURNAL KESEHATAN HUSADA GEMILANG
Publisher : STIKES HUSADA GEMILANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61129/jkhg.v8i2.125

Abstract

Teenagers often experience menstrual pain or dysmenorrhea caused by hormonal cycle instability and abnormalities in uterine contractions. The use of turmeric acid herbal remedy is believed to alleviate menstrual pain. Its phenolic compounds have antioxidant, analgesic, antimicrobial, and anti-inflammatory properties. The active compound curcumin can inhibit the enzyme cyclooxygenase, thereby reducing pain. The lack of knowledge among teenagers may discourage them from utilizing the turmeric acid herbal remedy. Counseling is one way to enhance knowledge; therefore, this study aims to determine the effect of counseling on the use of turmeric acid herbal remedy on the knowledge level of teenagers in Ngemplak Hamlet, Caturharjo, Sleman. This research uses a pre-experimental method with a pretest and posttest design, while the sampling technique employed is total sampling involving 60 female adolescent respondents. The research instrument consists of a questionnaire containing a list of questions, and the informational media used includes brochures and PowerPoint presentations. The results of the study show an average pretest score of 60.40 and a posttest score of 79.43, categorized as good. The results of the Wilcoxon statistical test show a p-value of 0.000 < 0.05, indicating that there is an effect of the counseling on the level of knowledge regarding the use of turmeric acid herbal medicine to address menstrual pain. Remaja lebih sering mengalami nyeri haid atau dismenorea yang disebabkan oleh ketidakstabilan siklus hormonal maupun abnormalitas konstraksi uterus. Penggunaan jamu kunyit asam dipercaya mampu mengatasi nyeri haid. Kandungan senyawa fenolik berkhasiat antioksidan, analgetik, antimikroba dan antiinflamasi. Senyawa aktif kurkumin mampu menghambat enzim siklooksigenase sehingga mampu mengurangi rasa nyeri. Kurangnya pengetahuan remaja akan mendorong keengganan untuk memanfaatkan jamu kunyit asam. Penyuluhan merupakan salah satu cara meningkatkan pengetahuan, oleh karena itu penelitian ini bertujuan untuk mengetahui pengaruh penyuluhan penggunaan jamu kunyit asam terhadap tingkat pengetahuan remaja Dusun Ngemplak, Caturharjo, Sleman. Penelitian ini menggunakan metode pre-eksperimental dengan desain pretes dan posttest, sedangkan Teknik pengambilan sampel secara total sampling sebanyak 60 responden remaja putri. Instrumen penelitian berupa kuisioner berisi daftar pertanyaan, media penyuluhan berupa brosur dan powerpoint. Hasil penelitian memberikan nilai rata-rata pretest dan posttest 60,40 serta nilai setelah penyuluhan menjadi 79,43 dengan kategori baik. Hasil uji statistic uji Wilcoxon menunjukkan p-value 0,000 <0,05 menunjukkan bahwa terdapat pengaruh penyuluhan terhadap tingkat pengetahuan dalam penggunaan jamu kunyit asam untuk mengatasi nyeri haid.
AKTIVITAS PENANGKAPAN RADIKAL DPPH OLEH FRAKSI N-HEKSAN DAN FRAKSI ETIL ASETAT DAUN KELOR (Moringa oleifera, Lamk) Erika, Beta Ria; Dellima, Marita; Sulistyawati, Rini
Media Farmasi: Jurnal Ilmu Farmasi Vol. 11 No. 1: Maret 2014
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v11i1.1392

Abstract

Radikal bebas dikenal sebagai mediator berbagai penyakit. Beberapa kandungan kimia  tumbuhan  seperti  senyawa  fenolik  dan  flavonoid  telah  dilaporkan berkorelasi  terhadap  aktivitas  penangkapan  radikal. Salah  satu  tanaman  yang berpotensi  sebagai  penangkap  radikal adalah  kelor (Moringa  oleifera  Lamk). Penelitian ini bertujuan untuk mengevaluasi aktivitas penangkapan radikal  bebas 2,2-difenil-1-pikrilhidrazil (DPPH)  fraksi n-heksan (fraksi non polar) dan fraksi etil asetat (fraksi polar).Serbuk daun kelor dimaserasi menggunakan etanol 80%, kemudian  pelarut  diuapkan. Ekstrak etanolik daun kelor selanjutnya difraksinasi menggunakan beberapa pelarut  dengan polaritas yang berbeda. Setiap fraksi yang dihasilkan  kemudian  diuji  aktivitas  penangkapan  radikal  DPPH menggunakan metode  spektrofotometri  tampak  pada  panjang  gelombang  517  nm.Kemampuan fraksi-fraksi  daun  kelor  dalam  menangkap  radikal  DPPH  diamati menggunakan parameter  IC 50. Fraksi etil asetat mempunyai  IC 50 kecil (6,59 ¼g/mL) dibanding fraksi  n-heksan  (77,80¼g/mL).Hal  ini  menunjukkan  bahwa  fraksi  etil  asetat mempunyai kemampuan  menangkap  radikal  bebas  DPPH  yang  lebih  besar diibandingkan fraksi heksana. Kata kunci : daun kelor, penangkapan radikal bebas, DPPH.
Co-Authors Ahmad Badawi Saluy Any Guntarti Beta Ria Erika Citra Ariani Edityaningrum, Citra Eka Rahayuningsih, Yuni Hidayati, Sholihatil Laela Hayu Nurani Marita Dellima Moch Saiful Bachri Muhammad Ma'ruf Murni Hartini, Windadari Puspitasari, Adellia Rizki Amelia Sulistyorini, Dwi Agustin