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All Journal Edukasi Journal of the Indonesian Tropical Animal Agriculture Asean Journal of Science and Engineering (AJSE)
S. Suryana
Assesment Institute for Agricultural Technology of South Kalimantan, Jl. Panglima Barat No. 4 Banjarbaru, South Kalimantan
Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Earth & Planetary Sciences Education Engineering Materials Science & Nanotechnology

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Journal : Asean Journal of Science and Engineering (AJSE)

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Hydroxyapatite as Delivery and Carrier Material: Systematic Literature Review with Bibliometric Analysis Noviyanti, Atiek Rostika; Adzkia, Qurratu Aini Alya; Novella, Indrika; Kurnia, Irwan; Suryana, S.; Ma'Amor, Azman Bin; Irwansyah, Ferli Septi
ASEAN Journal of Science and Engineering Vol 4, No 2 (2024): AJSE: September 2024
Publisher : Universitas Pendidikan Indonesia (UPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17509/ajse.v4i2.70223

Abstract

Hydroxyapatite (HA), a bioactive calcium phosphate compound, has garnered significant attention in biomedical and pharmaceutical research due to its remarkable properties as a delivery and carrier material. This review aims to comprehensively analyze the extensive research surrounding HA's applications in drug delivery and as a carrier for various therapeutic agents, encompassing various studies from scientific articles focusing on HA-based systems designed for drug delivery, tissue engineering, and other therapeutic applications. The review also investigates the HA synthesis and modification methods for tailored drug release profiles, as well as the interaction between HA and bioactive molecules. Key findings from the review include the versatility of HA as a biocompatible carrier, its ability to facilitate controlled drug release, and its potential to enhance tissue regeneration. The review identifies trends in HA-based delivery systems, highlighting recent advances and emerging research directions, as well as providing valuable insights into the current state of HA-based drug delivery and carrier materials, shedding light on the potential of HA to revolutionize the field of biomedicine. It serves as a valuable resource for researchers, clinicians, and pharmaceutical professionals seeking to harness the capabilities of HA in developing innovative therapeutic strategies.
Co-Authors Adzkia, Qurratu Aini Alya Atiek Rostika Noviyanti Kurnia, Irwan L.H. Prasetyo Ma'Amor, Azman Bin Novella, Indrika P.S. Hardjosworo R.R. Noor