Yoga I Kasjmir
Rheumatology Division of the Department of Internal Medicine, Faculty of Medicine of the University of Indonesia, Cipto Mangunkusumo National Central General Hospital

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Tophi which develop years before the first attack of acute gouty arthritis Rudy Hidayat; Yoga I Kasjmir
Indonesian Journal of Rheumatology Vol. 1 No. 1 (2009): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (200.678 KB) | DOI: 10.37275/ijr.v1i1.19

Abstract

Gout is a clinical disease associated with hyperuricemia and caused by the deposition ofmonosodium urate crystals in and around the tissue of joints. The course of classic gout passes through three distinct stages: asymptomatic hyperuricemia, acute intermittent gout, and advanced gout/chronic tophaceous gout.1,2 Tophi; described as accumulation of articular, osseus, soft tissue, and cartilaginous crystalline deposits; is one of clinical manifestation of chronic tophaceous gout stage, and usually developedafter 10 or more years of acute intermittent gout.1,2 Although patients have been reported with tophias their initial clinical manifestation