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Kevin Yonatan Budiman
Department of Internal Medicine, Faculty of Medicine, Padjadjaran University, Hasan Sadikin General Hospital.
Medicine & Pharmacology

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Successful Treatment of Primary Sjogren's Syndrome Associated with Interstitial Lung Disease Laniyati Hamijoyo; Kevin Yonatan Budiman; Reza Kurniawan Tanuwihardja
Indonesian Journal of Rheumatology Vol. 12 No. 1 (2020): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v12i1.143

Abstract

We report a rare case of interstitial lung disease as the first clinical manifestation of primary Sjögren’s syndrome. A 49-year-old woman was assessed, complaining of dyspnea, dry cough, dry mouth, inflamed right cheek, dry skin, bilateral gastrocnemius pain, multiple peripheral arthralgia, and generalized weakness for the previous 2 months. Serology examination was positive for Sjögren’s syndrome antibodies. Thorax CT demonstrated Crazy Paving appearance. Glucocorticoid alone did not improve the respiratory symptoms, hence azathioprine was given. Subsequent dyspnea regression and disease control obtained after 5 months of therapy. This case demonstrated that ILD could be the first clinical manifestation in pSS, and azathioprine could be used as the first line therapy for Sjögren’s syndrome-related lung disease.
Co-Authors Laniyati Hamijoyo Reza Kurniawan Tanuwihardja