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Nidhi Chaudhary
Department of Chemistry, I.I.M.T., I.E.T., Ganga Nagar, Meerut-250001, U.P.
Chemical Engineering, Chemistry & Bioengineering Chemistry

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SYDNONE DERIVATIVES A SYNTHONS FOR NOVEL MESOIONIC COMPOUNDS. SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF SOME 2-(4`-SUBSTITUTED ANILINOSYNDON-3`-YL)-1, 3, 4-THIADIAZINO (6, 5-B) INDOLES Hemant Panwar; Shishupal Singh; Nidhi Chaudhary
Indonesian Journal of Chemistry Vol 11, No 3 (2011)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (335.468 KB) | DOI: 10.22146/ijc.21380

Abstract

In the present study, a series of 2-(4´-Substitutedanilinosydnon-3´-yl)-1, 3, 4-thiadiazino (6, 5-b) indoles 7a-j have been synthesized. All the synthesized compounds have been characterized by elemental and spectral (I R, 1H- NMR and Mass) spectrometric analysis. Furthermore, above mentioned compounds were evaluated for their antibacterial and antifungal activities against selected panel of pathogenic strains. Ampicillin trihydrate, ofloxacin and fluconazole, griseofulvin were used as standard drugs for antibacterial and anifungal activity respectively. Compound 7j was found the most potent one with lesser toxicity in the prepared indole derivatives.
Co-Authors Hemant Panwar Shishupal Singh