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Euis Filaila
Research Center for Chemistry, Indonesian Institute of Sciences, Kawasan PUSPIPTEK, Serpong, Tangerang, Banten
Chemical Engineering, Chemistry & Bioengineering Chemistry

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ANTI DIABETIC FLAVANONE COMPOUND FROM THE LEAVES OF Artocarpus communis Puspa D.N. Lotulung; Sofa Fajriah; Andini Sundowo; Euis Filaila
Indonesian Journal of Chemistry Vol 9, No 3 (2009)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (156.149 KB) | DOI: 10.22146/ijc.21524

Abstract

The Flavanone compound with anti diabetic activity was isolated from ethyl acetate extract of Artocarpus communis leaves using column chromatography techniques. The structure of the flavanone compound was elucidated on the basic of spectroscopic evidence and comparison to published values. This compound, 8-geranyl-4,5,7-trihydroxyflavone, showed strong anti diabetic activity on α-glucosidase inhibition assay with IC50 18.120 µg mL-1.
Co-Authors Andini Sundowo Puspa D.N. Lotulung Sofa Fajriah