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Kyoko Adachi
Marine Biotechnology Institute,3-75-1 Heita, Kamaishi, Iwate 026-0001 Japan
Chemical Engineering, Chemistry & Bioengineering Chemistry

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ISOLATION OF ACTINOMYCIN D FROM MARINE DERIVED Streptomyces Abdullah Rasyid; Kyoko Adachi
Indonesian Journal of Chemistry Vol 7, No 3 (2007)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (249.493 KB) | DOI: 10.22146/ijc.21683

Abstract

The bioactive substance producing strain, a marine bacterium A5S-46 was found in the antibacterial screening. This strain was isolated from the artificial sponge set in the coastal seawater at Iriomote islands (Japan). The crude extract from culture broth of the strain A5S-46 was assayed to the antibacterial activity test against the seven kinds of bacterial test strains. The active substance accumulated in the both bacterial cells and culture supernatant. Based on the 1H NMR and the LC/PDA/MS data, the bioactive substance was identified to be actinomycin D.
Co-Authors Abdullah Rasyid