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Antonius Gelong
Farmasi, Poltekkes Kemenkes Kupang
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology

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Uji Aktivitas Antibakteri Ekstrak Etanol Kulit Batang Delima (Punica granatum. L)Terhadap Bakteri Staphylococus aureus ATCC 6538 Tahun 2016 Fatmawati Blegur; Antonius Gelong
JURNAL INFO KESEHATAN Vol 16 No 1 (2018): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Politeknik Kesehatan Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol16.Iss1.184

Abstract

Background: Pomegranate bark (Punica granatum, L) contains ellagitannin, triterpenoid, alkaloids consisting of pelletierine, methylpelletieren, pseudopelletierine, flavonoids, and saponins. Substances that are able to inhibit bacterial growth are saponins and flavonoids. Objective: to determine the antibacterial activity of ethanol extract of pomegranate bark (Punicagranatum, L) on the Staphylococcus aureus bacteria. Method: The manufacture of pomegranate bark extract was carried out using the Soxlhetasi method, after extracting the antibacterial activity was carried out by using a cylinder diffusion method. Result: Ethanol extract of pomegranate bark (Punica granatum, L) has antibacterial activity against Staphylococcus aureus bacteria at a concentration of 10% b / v, 25% b / v, 50% b / v and 75% b / v with each inhibition zone diameter -as equal to 18.70 mm, 21.00 mm, 22.30 mm and 26.20 mm. Stastically, ethanol extract of pomegranate bark (Punica granatum, L) has significant antibacterial power with p = 0.001 (p <0.05). Conclusion: Ethanol extract of pomegranate bark (Punica granatum, L) has antibacterial activity against Staphylococcus aureus bacteria with very strong concentration is a concentration of 25% b / v, 50% b / v and 75% b / v, because the inhibition zone is> 20 mm.
Co-Authors Fatmawati Blegur