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lidia lidia
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FORMULASI GEL EKSTRAK BUAH TOMAT DAN BENZOFENON SERTA UJI NILAI SPF lidia lidia
Jurnal Penelitian Farmasi Indonesia Vol. 6 No. 2: jpfi
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

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Abstract

The research of formulation gel preparation combination tomato extract (Solanum lycopersicum L.) and benzophenone. The research to know that the combination of tomato extract and benzophenone can be formulated into gel preparation with variation concentration carbopol 940 0,5%, 1%, and 1,5% as gel base. Then gel was evaluated, include observation of organoleptic, homogeneity, pH, viscosity, spreadability, freeze thaw test, iritation test, and for the most stable formula was determined SPF value by measuring absorbance sample at wavelength 290–320 nm with interval 5 nm using UV-Vis spectrophotometry. Results of the research showed that gel preparation of second formula was the most stableof the three with a typical smell tomato, yellow color, semisolid consistence, homogeneous, pH 5.73 ± 0.05, viscosity 4533 ± 115.47 cPs, has good spreadability, not irritating, and has SPF value28.61 ± 0.01.
FORMULASI EMULGEL SARI BUAH TOMAT DAN OCTYL METHOXYCINNAMATE SERTA UJI NILAI SPF lidia lidia
Jurnal Penelitian Farmasi Indonesia Vol. 6 No. 1 (2017): jpfi
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

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Abstract

Sunscreen is a preparation containing substances that can absorb and / or reflect back the exposed ultraviolet rays on the skin. The compounds commonly used as sunscreens are octyl methoxycinnamate which chemically absorbs UV light into the epidermal layer of the skin. However, this substance has a deficiency that is photolabil causing reduced efficacy of UV filters from sunscreen (Draelos & Thaman, 2006). Lycopene compounds in tomatoes are antioxidants that have photoprotective nature (Svobodova et al, 2003). Based on some previous research states that the content of lycopene in tomatoes (Solanum lycopersicum L.) can be used to protect the skin from ultraviolet radiation. The aim of this research is to know whether tomato’s extract and octyl methoxycinnamate can be formulated into emulgel and what is SPF value obtained from emulgel preparation of tomato’s extract combination and octyl methoxycinnamate. The emulgel was evaluated, including organoleptic examination, homogeneity, pH, viscosity, dispersion, freeze thaw test, irritation test, and for the most stable formula determined SPF value by measuring absorbance of sample solution at 290-320 nm wavelengths at interval 5 nm using a UV-Vis spectrophotometer. The results showed that the third emulgel formula has the best stability among the three formulas and has an SPF value of 29.32 ± 0.030 under the ultra-protection category.
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