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POTENSI EKSTRAK KULIT BUAH DELIMA TERHADAP PERTUMBUHAN Candida albicans SECARA IN VITRO jirna inyoman
Meditory : The Journal of Medical Laboratory Vol 5, No 2 (2017): meditory ,Volume 5, No 2, Desember 2017
Publisher : Jurusan Analisis Kesehatan, Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (232.875 KB) | DOI: 10.33992/m.v5i2.125

Abstract

AbstractBackground: Infection by the Candida albicans has increased globally and reported fungal resistance to synthetic antifungal. It is, therefore, necessary to develop effective antifungal medicines for the treatment of infection by Candida albicans. This study aims to determine the content of phytochemical and inhibitory power of pomegranate skin extract on Candida albicans growth. Methode: This research type is the true experiment with post test only control design. The method used for the phytochemical test is qualitative tube method. Pomegranate skin resistivity test on Candida albicans growth was done by disc diffusion method. The pomegranate skin is tested at concentrations of 100%, 75%, 50%, 25% and 10%. Negative control with 96% alcohol and positive control using ketocenazole 2%. Result: The results of phytochemical tests showed pomegranate skin extract containing saponins, tannins, and flavonoids. Pomegranate skin extracts are not able to inhibit the growth of Candida albicans by disc diffusion method.Conclusion:The conclusion of this study is pomegranate skin extracts can not inhibit Candida albicans growth, For other researchers which use jatropha curcas twigs, are suggested to do a phytochemical test quantitatively and to test the antifungal potential with liquid DMSO 10%, kloroform and petroleum eter..Keywords:Potential antifungal, pomegranate skin extract, Candida albicans
EFEK ANTI JAMUR AIR RENDAMAN DAUN KELOR (Moringa oleifera) TERHADAP PERTUMBUHAN JAMUR Trichophyton mentagrophytes SECARA IN VITRO jirna inyoman
Meditory : The Journal of Medical Laboratory Vol 5, No 1 (2017): Juni 2017 Meditory
Publisher : Jurusan Analisis Kesehatan, Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (214.89 KB) | DOI: 10.33992/m.v5i1.106

Abstract

Abstract Background Moringa oleifera is a plant that all parts can be used for medicinal purposes. Roots, flowers, bark, stems, leaves and seeds of Moringa has antimicrobial properties. Compound content in leaves of moringa, such as tannin,steroid, alkaloid, saponins ,and flavonoids . ObjectiveThe purpose of this research was to know the different of Trichophyton mentagrophytes growth on various leaves of moringa (Moringa oleifera) concentration extract. Methods This research uses a true experimental with post test only kontrol group design. The antifungal activity test use diffusion disk method, these were divided into four test group with concentration 25%, 50%, 75%, 100% and two kontrol group were positive kontrol (ketokonazole 2%) and negatif kontrol (sterile distilled water). The result of this study showed that the average diameter of inhibition zone of concentration 25% until 100% is 0 mm. Statistic analysis was done by using Kolmogorof Smirnov test and Kruskal Wallis test. The test showed there was not a significant mean difference between group. All consentration haven’t an effect on Trichophyton mentagrophytes growth inhibition zone diameter. For next research with same topics using pure extract leaves of moringa was recommended. Keywords: Inhibition zone, Moringa oleifera, Trichophyton mentagrophytes.