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PENGARUH EKSTRAK AKAR ENCOK TERHADAP PERTUMBUHAN STAPHYLOCOCCUS AUREUS igede sudarmanto
Meditory : The Journal of Medical Laboratory Vol 4, No 2 (2016): Desember 2016
Publisher : Jurusan Analisis Kesehatan, Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (225.823 KB) | DOI: 10.33992/m.v4i2.50

Abstract

Background: Resistance is defined as growth inhibition of bacteria with antibiotics. Staphylococcus aureus bacteria is known to be resistant to gentamicin and methicillin. Staphylococcus aureus can cause various infection of the skin, injuries, and system. Methods: This research is true-experimental with Posttest-Only Control Group Design and using Kirby-Bauer method by means of five concentration (20, 40, 60, 80, dan 100%). The negative control uses sterile distilled water, and the positive control uses Vancomycin 30 µg. Result: This research showed the mean of inhibition zone diameter of each concentration consecutively 16 mm, 20 mm, 22 mm, 23 mm, and 23 mm. Oneway ANOVA statistic analysis showed that the value of p is 0,000 that mean there is an influence of encok roots extract to Staphylococcus aureus growth. Conclusion: There is an influence of encok roots extract to Staphylococcus aureus growth. Seen from its ability to inhibit the growth of Staphylococcus aureus.
PERBEDAAN ZONA HAMBAT PERTUMBUHAN SALMONELLA TYPHI PADA BERBAGAI KONSENTRASI REBUSAN DAUN MIMBA SECARA IN VITRO igede sudarmanto
Jurnal Skala Husada : The Journal of Health Vol 19, No 2 (2022): Jurnal Skala Husada: The Journal of Health
Publisher : Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/jsh:tjoh.v19i2.2005

Abstract

Background Typhoid fever is one kind of typhoidal species group caused by infection of Salmonella Typhi. The general therapy of Salmonella Typhi is giving antibiotic. But giving it in the wrong dose can cause resistance of this bacteria. So, some people move to use traditional medicine to pretend the infection. One of plant that can use as alternative medicine is Azadirachta indica or neem. Neem leaf contain some substance such as quercetin and tannin that can use as antimicrobial.Objective to know about the effect of differences concentration of neem leaf boiled water on growth of Salmonella Typhi.Method The method of this research is true experiment with posttest only control design.Result There is zero zone of inhibition on concentration 20%, on 40% concentration is 4,9 mm of inhibition zone, on 60% is 7,8 mm of inhibition zone, on 80% is 9,1 mm of inhibition zone and on 100% is 11,1 mm of inhibition zone. The probability result testing by Anova is 0,000 0,05.Conclusion of this research is there are difference growth of Salmonella Typhi on different concentrate of neem leaf boiled water with in vitro inhibitionKeywords: neem leaf, Salmonella Typhi, inhibition