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All Journal PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia)
Tjiptasurasa Tjiptasurasa
Fakultas Farmasi, Universitas Muhammadiyah Purwokerto, Jl. Raya Dukuhwaluh, PO BOX 202, Purwokerto 53182
Materials Science & Nanotechnology

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AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL KAYU NANGKA (Artocarpus heterophylla Lmk.) TERHADAP Bacillus subtilis DAN Escherichia coli Refriana Setya Pratiwi; Tjiptasurasa Tjiptasurasa; Retno Wahyuningrum
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 08 No. 03 Desember 2011
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pji.v8i03.1125

Abstract

ABSTRAK Telah dilakukan penelitian tentang aktivitas antibakteri ekstrak etanol kayu nangka (A. heterophylla Lmk.) terhadap pertumbuhan bakteri B. subtilis dan E. coli secara in vitro. Ekstraksi kayu nangka dilakukan dengan metode maserasi menggunakan pelarut etanol 70%. Uji aktivitas antibakteri dilakukan dengan metode difusi agar. Ada 5 kelompok yang diujikan, yaitu konsentrasi 1%, konsentrasi 10%, konsentrasi 100%, kontrol positif (tetrasiklin HCl) dan kontrol pelarut/ kontrol negatif Dimetilsulfoksida (DMSO 10%). Hasil penelitian menunjukkan bahwa ekstrak etanol kayu nangka tidak memiliki aktivitas terhadap pertumbuhan bakteri uji sampai dengan kadar tertinggi. Hasil uji KLT menunjukkan bahwa ekstrak etanol kayu nangka mengandung flavonoid dan alkaloid. Kata kunci: antibakteri, ekstrak etanol kayu nangka (A. heterophylla Lmk.), Bacillus subtilis, Escherichia coli. ABSTRACT Research on antibacterial activity of jackfruit wood (A. heterophylla Lmk.) ethanolic extract to B. subtilis and E. coli in vitro have been done. Jackfruit wood extraction was done with maceration method using ethanolic solvent 70%. Antibacterial activity test used agar diffution method. There were tested 5 groups of serial extract concentration 1%, 10% and 100%; positive control (tetracycline HCl) and solvent control/ negative control Dimethylsulfoxide (DMSO 10%). The result showed that ethanolic extract of jackfruit wood didn’t have antibacterial activity until the highest concentration. Thin Layer Chromatography (TLC) test showed that ethanolic extract of jackfruit wood contain flavonoid and alkaloid. Keywords: antibacterial, ethanolic extract of jackfruit wood (A. heterophylla Lmk.), Bacillus subtilis, Escherichia coli.
Co-Authors Refriana Setya Pratiwi Retno Wahyuningrum