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Suzanny Dwi Ellita
Department of Chemistry, Faculty of Matematics and Natural Sciences, Institut Teknologi Bandung
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education

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p-Hydroxybenzoic Acid and Kaempferol from Desmodium Triquetrum Elvira Hermawati; Suzanny Dwi Ellita; Lia Dewi Juliawaty; Euis Holisotan Hakim
Jurnal Kartika Kimia Vol 3 No 1 (2020): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, Jenderal Achmad Yani University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (188.78 KB) | DOI: 10.26874/jkk.v3i1.51

Abstract

Desmodium triquetrum (Fabaceae) is widely distributed in Indonesia and used as herbal medicines for diuretic, hemorrhoids, tonics, and anti-inflammatory. Two known compounds, p-hydroxybenzoic acid (1) and kaempferol (2), were isolated from the MeOH extract of the leaves of Desmodium triquetrum. The structures of isolated compounds were determined based on 1H and 13C NMR data. The MeOH extract showed very active with 6,5 μg/mL in addition, compound (1) and (2) showed weak cytotoxicity against murine cell leukemia P-388 with IC50 55,0 and 24,7 μg/mL, respectively. Compound (1) was the first reported in this species.Keywords: Desmodium triquetrum, kaempferol, p-hydroxybenzoic acid
Co-Authors Elvira Hermawati Euis Holisotan Hakim Lia Dewi Juliawaty