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All Journal BIOVALENTIA: Biological Research Journal
Salni Salni
Department of Biology, Faculty of Mathematics & Natural Sciences, Sriwijaya University, Palembang-Prabumulih Highway km 32, Indralaya, Indonesia.
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Environmental Science Immunology & microbiology Medicine & Pharmacology

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ANTIOXIDANT ACTIVITY OF TEMBESU (Fagraea fragrans Roxb.) LEAF Budi Eko Wahyudi; Salni Salni; Arum Setiawan
BIOVALENTIA: Biological Research Journal Vol. 8 No. 2 (2022)
Publisher : Biology Department, Faculty of Mathematics and Natural Sciences, Sriwijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24233/biov.8.2.2022.250

Abstract

Herbal medicine is becoming a trend in curing several diseases especially degenerative because of the bad effects of synthetic drugs. Tembesu plant (Fagraea fragrans Roxb.) is traditionally used for degenerative diseases. This study aims to separate bioactive compounds (active fraction), pure isolate compounds from tembesu leaf, then observe antioxidant activity. The methods used are maceration extraction, liquid-liquid fractionation, purification of compounds by gravity chromatography column and antioxidant activity by scavenging DPPH radicals. The results showed that the active antioxidant fractions were n-hexane and ethyl acetate fractions. The results of purification of antioxidant compounds, obtained 6 isolates N1, N2, N4, N5, E8 and E11. Antioxidant activity (IC50) of pure isolates N1 (13.72 ppm), N2 (28.93 ppm), N4 (110.44 ppm), N5 (177.23 ppm), E8 (82.50 ppm) and E11 (12 ,86 ppm). The antioxidant compounds that have been isolated are terpenes (N1, N2, N4, E8), phenols (N5) and flavonoids (E11). This study concluded that tembesu leaf have antioxidant potential. Antioxidant bioactive compounds in tembesu leaf have the potential to be developed into standardized herbs and phytopharmaceuticals.
Co-Authors Arum Setiawan Budi Eko Wahyudi