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All Journal Journal Pharmaceutical Science and Application (JPSA)
Ida Ayu Nadia Kusumastuti
Udayana University
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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ACTIVITY OF BAY LEAF EXTRACT (Eugenia polyantha) AS ANTI-INFLAMMATORY IN WHITE RAT (Rattus norvegicus) Ida Ayu Nadia Kusumastuti; Made Krisna Adi Jaya
Journal Pharmaceutical Science and Application Vol 4 No 1 (2022): Journal Pharmaceutical Science and Application
Publisher : Departement of Pharmacy, Faculty of Mathematic and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2022.v04.i01.p04

Abstract

Background: Inflammation is the body's defense response against foreign body invasion, tissue injury, or both caused by microorganisms, mechanical trauma, chemical compounds, and physical factors. Anti-inflammatory agents can be used to treat inflammation. Bay leaves are one example of a plant that can be used. Ethanol extract and water extract of a bay leaf can be anti-inflammatory because they contain flavonoids. Objectives: The purpose of this study was to see how effective ethanol extract and aqueous extract of bay leaf were as anti-inflammatory agents in mice. Methods: This study employs a systematic literature review approach, descriptive qualitative research, and library research. Results: The most efficacious dose was 150 mg/kg BW at a 70 percent concentration and at an 80 percent concentration for ethanol extract of bay leaves, and 50 mg/kg BW for the aqueous extract of bay leaves. Conclusion: Based on the results of this study, it can be concluded that bay leaf (Eugenia polyantha) ethanol extract and aqueous extract have anti-inflammatory activities Keywords: Anti-inflammatory, Bay Leaf, Diclofenac sodium, Ethanol Extract, Aqueous
Co-Authors Made Krisna Adi Jaya