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All Journal Jurnal Anestesiologi Indonesia
Yulia Wahyu Villyastuti
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Health Professions Medicine & Pharmacology Public Health

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Comparison of Laryngeal Mask Airway and Endotracheal Tube on Intraocular Pressure in Vitrectomy Villyastuti, Yulia Wahyu; Wicaksono, Indrawan
JAI (Jurnal Anestesiologi Indonesia) Vol 16, No 3 (2024): JAI (Jurnal Anestesiologi Indonesia)
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.65469

Abstract

Background: Increased intraocular pressure (IOP) is a common complication after vitrectomy. Tracheal intubation and insertion of a laryngeal mask airway (LMA) are noxious stimuli that can increase IOP.Objective: To analyze the difference between the use of LMA and an endotracheal tube (ETT) on the increase in IOP in vitrectomy.Method: Experimental study with a randomized controlled trial design in 28 patients undergoing vitrectomy who met the inclusion and exclusion criteria. Subjects were divided into 2 groups with the use of LMA and ETT. Intraocular pressure (IOP) was measured using a Schiotz tonometer before induction of anesthesia, 5 minutes after intubation, 5 minutes before extubation, 5 minutes after extubation and 24 hours after vitrectomy in healthy eyes. The analysis was carried out with the unpaired T-test and the alternative Mann Whitney test, the results were significant if the p value <0.05.Results: The mean IOP in the LMA group was 11.71 ± 1.90 mHg before induction of anesthesia; 11.04 ± 1.71 mmHg 5 min after induction; 10.86 ± 1.44 mmHg 5 min before discharge; 12.11 ± 1,49 mmHg after removal and 12.21 ± 2.63 mmHg 24 hours after discharge. The mean IOP in the ETT group was 11.05 ± 2.57 mHg before induction of anesthesia; 14.26 ± 2.59 mmHg 5 min after induction; 11.71 ± 1.90 mmHg 5 min before extubation; 14.70 ± 0,98 mmHg after extubation and 12.74 ± 1.82 mmHg 24 hours after extubation. A significant difference in IOP was found after ETT intubation and extubation (p < 0.05).Conclusion: Endotracheal tube (ETT) significantly increases IOP compared to LMA during intubation and extubation in vitrectomy surgery.
Pengaruh Anestesi Epidural Terhadap Supresi Imun Yang Diinduksi Stres Operasi Selama Pembedahan Yudhowibowo, Ifar Irianto; Sutiyono, Doso; Villyastuti, Yulia Wahyu
JAI (Jurnal Anestesiologi Indonesia) Vol 3, No 1 (2011): JAI (Jurnal Anestesiologi Indonesia)
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v3i1.6453

Abstract

Operasi besar berhubungan dengan disfungsi sistem kekebalan tubuh bawaan. Baru-baru ini, dibuktikan bahwa stres akibat pembedahan dapat dengan cepat menginduksi penurunan respon sementara dari darah terhadap endotoksin sejak 2 jam setelah insisi dan bahwa IL-10 plasmayang meningkat selama pembedahan, berperan dalam penurunan respon ini. Telah dilaporkan bahwa anestesi epidural memiliki efek menguntungkan pada reaksi imunitas dan respon terhadap stres akibat pembedahan. Beberapa peneliti telah melaporkan bahwa anestesi epidural mempertahankan aktivitas sel NK dan mengurangi respon stres pada pasien yang menjalani histerektomi. Blok epidural dari segmen dermatom T4 sampai S5, dimulai sebelum pembedahan, mencegah peningkatan konsentrasi kortisol dan glukosa pada histerektomi. Teknik anestesi regional untuk operasi besar dapat mengurangi pelepasan kortisol, adrenalin (epinefrin) dan hormon lain, namun memiliki pengaruh kecil pada respon sitokin. Penelitian terbaru (kawasaki et al.,2007) menunjukkan bahwa sistem kekebalan tubuh bawaan, misalnya fagositosis, ditekan oleh stres akibat pembedahan dan bahwa anestesi epidural tidak mampu mencegah penurunan respon kekebalan tubuh ini selama operasi perut bagian atas.
Co-Authors Doso Sutiyono Ifar Irianto Yudhowibowo Wicaksono, Indrawan