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Catarina Budyono
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Tinjauan Pustaka: Pengaruh Vitamin C, Vitamin D, dan Zinc Terhadap COVID-19 Eva Hiikmatul Damayanti; Catarina Budyono
Unram Medical Journal Vol 10 No 4 (2021): Jurnal Kedokteran Volume 10 nomor 4 (Desember) 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i4.597

Abstract

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is an emerging, highly contagious and pathogenic coronavirus. To date, there is no definitive therapy for SARS-Cov-2 infection known as COVID-19. Supportive therapy that can be done is the provision of vitamin and mineral supplementation by consuming vitamin C, vitamin D, and zinc. Several studies have shown that oral and intravenous administration of vitamin C can reduce the increased risk of complications, reduce severity, improve symptoms and improve prognosis with COVID-19. Zinc might reduce the risk of SARS-CoV-2 infection and shorten the duration and severity of illness.
Treatment options for unresectable hepatocellular carcinoma Catarina Budyono; Ainun Fatiha DP; Baiq Aliza K.I; I Gede Prabananda A
Unram Medical Journal Vol 10 No 4 (2021): Jurnal Kedokteran Volume 10 nomor 4 (Desember) 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i4.604

Abstract

Hepatocellular carcinoma (HCC) is a primary liver cancer that occurs due to the abnormal growth of hepatocytes. HCC is one of the cancers with the highest prevalence and incidence in the world. The main risk factors for HCC in Indonesia are chronic infection with hepatitis B virus, hepatitis C virus, and liver cirrhosis. The selection of the appropriate treatment modality for each patient is based on several patient-specific characteristics, such as tumor size, location, portal vein thrombosis, and liver function. Treatment options for unresectable hepatocellular carcinoma include intra-arterial therapy, multikinase inhibitors, and immunotherapy. Determining the stage is an important part of managing HCC because it can determine the treatment. One of the staging systems is the Barcelona Clinic Liver Cancer (BCLC) which categorizes HCC into 5 stages. Clinical severity criteria with BCLC stage are often used because they have good validity in predicting the prognosis of HCC patients.