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All Journal Jurnal Ilmu Kefarmasian Indonesia Jurnal Sabdariffarma: Jurnal Ilmiah Farmasi Kartika : Jurnal Ilmiah Farmasi
Yulia Wardati
Jurusan Farmasi Fakultas MIPA Universitas Al-Ghifari
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

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Pharmacoeconomic Analysis Of Using Cephalosporin Group In Appendicitis Prophylactic In Rumah Sakit Umum Daerah Subang Yulia Wardati; Dytha Andri Deswat; Zainal Muttaqin
JURNAL ILMU KEFARMASIAN INDONESIA Vol 16 No 2 (2018): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (277.253 KB) | DOI: 10.35814/jifi.v16i2.441

Abstract

The administration of cephalosporin group antibiotics in patients with post-surgical appendicitis is necessary to prevent postoperative wounds. This pharmacoeoconomic study was conducted retrospectively in the period of 1 January to 31 December 2015 in RSUD Subang for the purpose of determining the effectiveness of drugs and the cost of antibiotic use of ceftriaxone, cefotaxime, and ceftizoxime injection by Cost Effectiveness Analysis method. The subject of the patient was 78 people. Based on Average Cost Effectiveness Ratio (ACER), the smallest value is ceftriaxone Rp 729.124 / day, while the result of Cost Effectiveness plane with cefotaxime as standard drug, ceftriaxone occupies quadrant IV and ceftizoxime occupies quadrant I. The result of Incremental Cost Effectiveness Ratio (ICER) calculation obtained by difference of value equal to Rp 106.347 / day hence can be concluded that antibiotic injection of cefotaxime as standard injection antibiotics used by RSUD Subang can be replaced by antibiotic injection of ceftizoxim by adding cost Rp 106.347 / day but need attention to resource especially funds owned and should be selected if sufficient resources are available.
EVALUASI UPAYA PENGOBATAN SENDIRI (SWAMEDIKASI) MENGGUNAKAN OBAT ANALGETIKA-ANTIPIRETIKA PADA MASYARAKAT DESA JERUJU BESAR KALIMANTAN BARAT Yulia Wardati
Jurnal Sabdariffarma Vol 10, No 1 (2022): SABDARIFFARMA
Publisher : Prodi Farmasi - Universitas Al Ghifari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53675/jsfar.v10i1.482

Abstract

Self-medication requires a good knowledge in order to run well. This study was conducted to determine the relationship and strength of the relationship in the selection of antipyretic analgesic drugs associated with age, education and occupation by the people of Jeruju Besar Village. This type of research is non-experimental with a questionnaire tool. Sampling using purposive sampling method. Respondents in this study were 378 respondents. The results showed that the people of Jeruju Besar Village were right in choosing the medicine for fever, headache and pain. Respondents received information on drug selection through health workers by 58.7% and the reasons for self-medication to recover quickly were 74%. The majority of respondents aged 40 years 52.6%, while the level of education is moderate - high 52.4%. Based on the Multiple Correlation test the strength of the relationship was obtained Perfect Correlation or perfect knowledge (0.981) and education (0.872), Strong Correlation occupation (0.698) and age (0.633). The conclusion of this study is that there is a relationship between the level of education, knowledge, on the use of antipyretic analgesic drugs.
EVALUASI KEPUASAN PASIEN TERHADAP APOTEK X DAN Y DI KOTA PONTIANAK Yulia Wardati; Soni Spinnori; Ida Erna Widiyawati
Jurnal Sabdariffarma Vol 11, No 1 (2023): SABDARIFFARMA
Publisher : Prodi Farmasi - Universitas Al Ghifari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53675/jsfar.v11i1.1092

Abstract

The location of the X and Y Pharmacies are close together on one road in the Pontianak Kota sub-district, the service looks the same, but the number of consumers who come is more dominant at the X Pharmacy. To be able to measure the quality of service, it is necessary to evaluate customer satisfaction. This study aims to determine patient satisfaction, assess the relationship between patient characteristics and determine the strength of the relationship characteristics and 5 dimensions to the services of Pharmacy X and Pharmacy Y. The survey was conducted using a cross sectional approach using a validated questionnaire instrument. The level of customer satisfaction was measured using the SERVQUAL (Service Quality) model for 5 dimensions of service quality, namely reliability, responsiveness, assurance, empathy, and tangible. Respondents in this study were 106 respondents to pharmacy X, while 102 respondents to pharmacy Y. using the method Based on 5 dimensions of service quality the overall average value of 5 dimensions at pharmacy X is 87.5%, while the overall average value of 5 dimensions at pharmacy Y is 56.5%. Based on the che-square test analysis, the value of the relationship between patient characteristics and pharmaceutical services at pharmacies X and Y was obtained, namely at pharmacy X there was a relationship between work (p-value = 0.016) and education (p-value = 0.047) but only work factor (p-value = 0.014) which had a relationship to patient assessment at pharmacy Y. 48, at the pharmacy Y 0.682. In conclusion, in general the patient satisfaction of the studied Pharmacy X was "Very Satisfied", while the patient satisfaction of the studied Pharmacy Y was close to "Quite Satisfied". There is a relationship between work and education on the assessment of patients at pharmacy X, but only the occupational factor has a relationship with the assessment of patients at pharmacy Y. The strength of the characteristic relationship at pharmacies X and Y is strong, but the strength of the relationship based on 5 dimensions at pharmacy X is very strong, while at pharmacy Y it is strong.
UJI AKTIVITAS ANTIDIABETES MELITUS TIPE II INFUS BUAH KESEMEK (Diospyros kaki Linn.) TERHADAP TIKUS JANTAN PUTIH GALUR WISTAR Yulia Wardati; Dytha Andri Deswati; Idayati Idayati
Kartika : Jurnal Ilmiah Farmasi Vol 2 No 2 (2014)
Publisher : Fakultas Farmasi Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/kjif.v2i2.31

Abstract

Pengobatan diabetes mellitus tipe II dapat dilakukan dengan menggunakan bahan alam, seperti buah kesemek, yang mengandung beberapa metabolit sekunder, diantaranya polifenol. Penelitian dilakukan pada 3 kelompok tikus jantan putih galur Wistar berumur 3 bulan dengan dosis yang berbeda (22,5 mg/kg BB, 45 mg/kg BB dan 90 mg/kg BB) dengan menggunakan kontrol positif glukosa, kontrol negatif aquadest dan pembanding glibenklamid.metode yang digunakan adalah GOD-PAP (Glucose Oxidase-Phenol 4-Aminoantipirin). Dari hasil penelitian, dapat diketahui bahwa ketiga dosis infus buah kesemek (Diospyros kaki Linn.) yang digunakan menunjukkan adanya efek menurunkan kadar gula darah yang berbeda nyata secara statistik dengan taraf nyata α=0,05. Dosis sediaan uji yang paling efektif dalam menurunkan kadar gula darah tikus hiperglikemik adalah dosis III 90 g/kg BB tikus dengan taraf nyata α=0,05. Penelitian ini merupakan pembuktian penggunaan buah kesemek secara empiris. Penggunaan buah kesemek dapat digunakan untuk antidiabetik karena terbukti dalam penelitian dapat menurunkan kadar glukosa dalam darah tikus.
EFEKTIVITAS OBAT ANTIBIOTIK UNTUK DEMAM TIFOID TERHADAP PASIEN ANAK DI RUMAH SAKIT UMUM DAERAH dr. AGOESDJAM KABUPATEN KETAPANG KALIMANTAN BARAT PERIODE 2019 Wardati, Yulia
Jurnal Sabdariffarma: Jurnal Ilmiah Farmasi Vol 12, No 1 (2024): SABDARIFFARMA
Publisher : Prodi Farmasi - Universitas Al Ghifari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53675/jsfar.v12i1.481

Abstract

Typhoid fever is the third of the 10 main diseases in patients treated in hospitals in Indonesia, while at RSUD dr. Agoesdjam West Kalimantan is ranked fourth. The aim of the research is to determine patterns of drug use and evaluate the effectiveness of antibiotic drugs for patients with thiophid fever at RSUD dr. Agoesdjam. This research is an observational study with retrospective data collection in May-July 2019, with a total of 103 patients. The inclusion criteria taken were medical record data from patients aged 5 to 10 years, who were diagnosed with typhoid fever at the inpatient installation of the Regional General Hospital ( RSUD) Dr. Agoesdjam Ketapang, West Kalimantan. Exclusion criteria are; Medical records for typhoid fever patients have other comorbidities such as kidney failure, psychiatric disorders, and so on.The parameters for the effectiveness of the drugs used are LoS, LoSAR, reduction in body temperature and reduction in the number of leukocytes. The results obtained were the use of antibiotics including chloramphenicol, ampicillin, ceftriaxone and cefixime. Based on LoS parameters, ceftriaxone was the most effective (2.77 days), LoSAR ceftriaxone (5 days), decreased body temperature ampislin (4.2 °C) and decreased leukocytes ampislin (6075 cells per micro liter). The most antibiotic used was chloramphenicol (41 patients). The most effective drugs were ceftriaxone (according to LoS and LoSAR parameters) and ampicillin (according to body temperature and leukocyte reduction parameters). 
UJI AKTIVITAS ANTIDIABETES EKSTRAK METANOL DAUN KESUM PADA MENCIT YANG DIINDUKSI GLUKOSA Hidayati, Tita Khosima; Firdaus, Islami Nur; Wardati, Yulia
Jurnal Sabdariffarma: Jurnal Ilmiah Farmasi Vol 12, No 2 (2024): SABDARIFFARMA
Publisher : Prodi Farmasi - Universitas Al Ghifari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53675/jsfar.v12i2.1418

Abstract

Daun kesum merupakan tanaman khas Kalimantan Barat. Ekstrak daun kesum diduga berpotensi sebagai antidiabetes karena mengandung senyawa alkaloid, flavonoid, dan tanin. Senyawa tersebut dapat menghambat enzim α-glukosidase sehingga dapat menurunkan kadar glukosa darah. Penelitian ini bertujuan untuk mengetahui apakah ekstrak metanol daun kesum memiliki aktivitas antidiabetes. dan untuk mengetahui berapa dosis yang efektif untuk menurunkan kadar glukosa darah. Uji ini dilakukan secara in vivo terhadap mencit jantan yang diinduksi oleh glukosa. Setelah diinduksi pemberian dosis ekstrak diberikan dengan 3 dosis yaitu 50mg/kgBB, 100mg/kgBB, 150mg/kgBB. Pengecekan kadar glukosa darah dilakukan pada menit ke 30, 60, 90, dan 120 setelah pemberian larutan uji. Persentase penurunan kadar glukosa darah setelah pemberian larutan uji secara berurutan dari dosis 1 sampai 3 adalah 31.38%, 34.35%. dan 35,83% ini menunjukan bahwa ada penurunan kadar glukosa darah awal sampai menit 120. Dari penelitian ini dapat disimpukan bahwa ekstrak metanol daun kesum memiliki aktivitas antidiabetes dan berdasarkan uji statistik dengan metode Anova, sig 0, 589 (p 0.05), artinya semua kelompok perlakuan memiliki rata-rata kadar glukosa darah yang sama atau tidak ada perbedaan secara signifikan dari masing-masing dosis uji.
Co-Authors Dytha Andri Deswat Dytha Andri Deswati Dytha Andri Deswati, Dytha Andri Firdaus, Islami Nur Hidayati, Tita Khosima Ida Erna Widiyawati Idayati Idayati Idayati Idayati, Idayati Soni Spinnori Zainal Muttaqin