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Wasilah Rochmah Wasilah Rochmah
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Aged and Aging Wasilah Rochmah, Wasilah Rochmah
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 33, No 04 (2001)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (161.38 KB)

Abstract

Since the last two decades the history has witnessed that aging and gerontology have been the focus of extensive discourse and concern. Aging has arrived as an issue and object of study, and academic community recognized aging as a legitimate area of study. As the number of elderly has increased exponentially, the professional and paraprofessional occupations dealing with that problems of the elderly has also increased. Chronologically, a person is considered to be old if he/she experiences a long life. Old is not only viewed by its chronological aspect, but also by its physical and psychological aspects as well. Aging results in body structural and functional changes, and it generates impairment, disability, and sometimes conform to a disease. The mechanisms and factors underlying aging process are still controversial. In attempts to explain aging process some numbers of theories have been proposed. It is, therefore, the emerging issues concerning old and aging process are: how the aging process takes place and which theories are still plausible? Aging process is a life-long process, characterized by body- failures in maintaining homeostatic conditions to physiological stresses. There are a variety of theories of aging that are proposed in which some of them are still plausible.Keywords: elderly - aging process - body structural & functional changes - impairment & disability -theories of aging
The relationship between blood pressure and anthropometric measurements of junior high school students in the Municipality of Yogyakarta Wasilah Rochmah, Wasilah Rochmah
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 16, No 02 (1984)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (175.04 KB)

Abstract

The relationship between blood pressure and body weight, body height, and other anthropometric measurements, i, e,, upper arm circumference and fat thickness, was studied in 280 junior high school students, aged 12-17 years. Blood pressure was measured by using mercury sphygmomanometer; measurements were conducted once in the sitting position, and the subjects were considered to be normal based on the physical diagnostic examination. The results found showed that there are correlations between either systolic or diastolic blood pressure with anthropometric meas• ;urements. Since upper arm circumference indicates the muscle, bone and fat components of the body mass, further study is needed to determine which component has the highest correlation with blood pressure.Key Words: blood pressure - adolescence - anthropometry - nutrition - body mass
The glucose uptake velocity and ability of target tissue cells in the elderly men (in vivo) Wasilah Rochmah, Wasilah Rochmah
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 34, No 03 (2002)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (224.277 KB)

Abstract

Background: Age is one of the impaired glucose tolerance risks. Impaired glucose tolerance may be caused by the decrease of pancreatic B cells insulin secretion, or by the decrease of target tissue cell glucose uptake. Glucose tolerance tests which were conducted in the elderly, showed that plasma insulin concentrations at 120th minute were still higher than at minute-0 (at fasting time), while blood glucose levels were still high. It generated an impression that insulin inefficiency exist in the elderly.Objective: To reveal that the cause of insulin inefficiency in the elderly is due to the decrease of target tissue cell glucose uptake velocity and/or in decrease uptake ability.Methods: Elderly men subjects and young men comparable controls were given 130mU/kg L8M/hour insulin and 20g% dextrose infusion, while blood glucose level have to be maintained in euglycemic situations (euglycemic clamp test). In 30 minutes with stable blood glucose level, the amount of 20% dextrose infusion were calculated as glucose uptake in 30 minute (euglycemic clamp time). From this results the glucose uptake velocity and ability (glucose uptake ability = ratio between glucose uptake velocity and plasma insulin concentration = insulin sensitivity index) between the elderly and the young men were compaired by t-test.Results: Euglycemic clamp tests were conducted to 4 elderly men of 65-74 years old, and 4 young men of 21-30 years old as controls. The results showed that the velocity of glucose uptake by the target tissue cells in those elderly men were significantly (p<0.05) lower (10.08 f 2.34 mg/kg LBM/min.) than young men group (17.78 ± 5.49 mg/kg LBMlmin.). One elderly men showed the lowest difference (0) of insulin sensitivity index compared to one control subject. In the remaining three (75%) subjects the average of insulin sensitivity index (0.11 f 0.03) showed a significant difference (p<0.05) compared to young men group 10.19 f 0.04).Conclusions: The result of this study indicated that the cause of insulin inefficiency in the elderly men was due to the decrease of glucose uptake velocity and ability.Key words: impaired glucose tolerance - pancreas B cells insulin secretion - velocity of glucose uptake ability of glucose uptake - euglycemic clamp technique.
The glucose uptake velocity and ability of target tissue cells in the elderly men (in vivo) Wasilah Rochmah Wasilah Rochmah
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 34, No 03 (2002)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (224.277 KB)

Abstract

Background: Age is one of the impaired glucose tolerance risks. Impaired glucose tolerance may be caused by the decrease of pancreatic B cells insulin secretion, or by the decrease of target tissue cell glucose uptake. Glucose tolerance tests which were conducted in the elderly, showed that plasma insulin concentrations at 120th minute were still higher than at minute-0 (at fasting time), while blood glucose levels were still high. It generated an impression that insulin inefficiency exist in the elderly.Objective: To reveal that the cause of insulin inefficiency in the elderly is due to the decrease of target tissue cell glucose uptake velocity and/or in decrease uptake ability.Methods: Elderly men subjects and young men comparable controls were given 130mU/kg L8M/hour insulin and 20g% dextrose infusion, while blood glucose level have to be maintained in euglycemic situations (euglycemic clamp test). In 30 minutes with stable blood glucose level, the amount of 20% dextrose infusion were calculated as glucose uptake in 30 minute (euglycemic clamp time). From this results the glucose uptake velocity and ability (glucose uptake ability = ratio between glucose uptake velocity and plasma insulin concentration = insulin sensitivity index) between the elderly and the young men were compaired by t-test.Results: Euglycemic clamp tests were conducted to 4 elderly men of 65-74 years old, and 4 young men of 21-30 years old as controls. The results showed that the velocity of glucose uptake by the target tissue cells in those elderly men were significantly (p<0.05) lower (10.08 f 2.34 mg/kg LBM/min.) than young men group (17.78 ± 5.49 mg/kg LBMlmin.). One elderly men showed the lowest difference (0) of insulin sensitivity index compared to one control subject. In the remaining three (75%) subjects the average of insulin sensitivity index (0.11 f 0.03) showed a significant difference (p<0.05) compared to young men group 10.19 f 0.04).Conclusions: The result of this study indicated that the cause of insulin inefficiency in the elderly men was due to the decrease of glucose uptake velocity and ability.Key words: impaired glucose tolerance - pancreas B cells insulin secretion - velocity of glucose uptake ability of glucose uptake - euglycemic clamp technique.
Aged and Aging Wasilah Rochmah Wasilah Rochmah
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 33, No 04 (2001)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (161.38 KB)

Abstract

Since the last two decades the history has witnessed that aging and gerontology have been the focus of extensive discourse and concern. Aging has arrived as an issue and object of study, and academic community recognized aging as a legitimate area of study. As the number of elderly has increased exponentially, the professional and paraprofessional occupations dealing with that problems of the elderly has also increased. Chronologically, a person is considered to be old if he/she experiences a long life. Old is not only viewed by its chronological aspect, but also by its physical and psychological aspects as well. Aging results in body structural and functional changes, and it generates impairment, disability, and sometimes conform to a disease. The mechanisms and factors underlying aging process are still controversial. In attempts to explain aging process some numbers of theories have been proposed. It is, therefore, the emerging issues concerning old and aging process are: how the aging process takes place and which theories are still plausible? Aging process is a life-long process, characterized by body- failures in maintaining homeostatic conditions to physiological stresses. There are a variety of theories of aging that are proposed in which some of them are still plausible.Keywords: elderly - aging process - body structural & functional changes - impairment & disability -theories of aging
The relationship between blood pressure and anthropometric measurements of junior high school students in the Municipality of Yogyakarta Wasilah Rochmah Wasilah Rochmah
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 16, No 02 (1984)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (175.04 KB)

Abstract

The relationship between blood pressure and body weight, body height, and other anthropometric measurements, i, e,, upper arm circumference and fat thickness, was studied in 280 junior high school students, aged 12-17 years. Blood pressure was measured by using mercury sphygmomanometer; measurements were conducted once in the sitting position, and the subjects were considered to be normal based on the physical diagnostic examination. The results found showed that there are correlations between either systolic or diastolic blood pressure with anthropometric meas• ;urements. Since upper arm circumference indicates the muscle, bone and fat components of the body mass, further study is needed to determine which component has the highest correlation with blood pressure.Key Words: blood pressure - adolescence - anthropometry - nutrition - body mass
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