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All Journal Narra J Journal of Medical Science; Jurnal Ilmu Medis Rumah Sakit Umum Daerah dr. Zainoel Abidin, Banda Aceh
Nina Widasari
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Correlation between high sensitivity C reactive protein (Hs-CRP) and neutrophil-to-lymphocyte ratio (NLR) with functional capacity in post COVID-19 syndrome patients Widasari, Nina; Heriansyah, Teuku; Ridwan, Muhammad; Munirwan, Haris; Kurniawan, Ferry D.
Narra J Vol. 3 No. 2 (2023): August 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v3i2.183

Abstract

Post coronavirus disease 2019 (COVID-19) syndrome is one of the causes of reduced functional capacity and work productivity, in particular for healthcare workers. The pathophysiology of the post COVID-19 syndrome is related to complex and multisystem inflammatory mechanisms, and cardiopulmonary exercise rehabilitation program is one of the efforts to improve the recovery process for patients with post COVID-19 syndrome. The aim of this study was to determine the correlation between the level of high sensitivity C-reactive protein (Hs-CRP) and neutrophil-to-lymphocyte ratio (NLR) with functional capacity (VO2max) in individuals with post-COVID-19 syndrome who received moderate- and high-intensity supervised cardiopulmonary exercise. A prospective cohort study was conducted at the Integrated Cardiac Rehabilitation Center of Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia. The supervised cardiopulmonary exercise was conducted for six weeks according to the participant's baseline VO2max. Spearman's and Pearson's correlation tests were used to assess the correlations. A total of 30 individuals (19 and 11 had moderate and high intensity exercise, respectively) were involved in this study. At moderate intensity exercise, the average Hs-CRP and NLR were 3.3 mg/L and 1.99, respectively; while at high intensity, the values were 3.8 mg/L and 1.79, respectively. No significant correlation between Hs-CRP level and functional capacity in both moderate-intensity and high intensity groups. In contrast, NLR was negatively correlated with functional capacity (r=-0.545, p=0.016) in moderate intensity exercise group. In conclusion, NLR value was negatively correlated with functional capacity in individuals with post-COVID-19 syndrome after receiving moderate intensity supervised cardiopulmonary exercise program. Therefore, moderate intensity of cardiopulmonary exercise maybe be used as a program to accelerate the recovery for those with post COVID-19 syndrome.
Pengaruh Latihan Jantung Paru Terstruktur Pada Tenaga Kesehatan Dengan Sindroma Pasca COVID – 19 Terhadap Peningkatan Kapasitas Fungsional Teuku Heriansyah; Muhammad Ridwan; Nina Widasari
Journal of Medical Science Vol 2 No 2 (2021): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (334.487 KB) | DOI: 10.55572/jms.v2i2.51

Abstract

COVID-19 is a multisystem disease, with various complications besides respiratory disorders that can affect various systems ranging from the heart, kidneys, gastrointestinal, nervous, endocrine, and musculoskeletal. Post COVID-19/Long Covid Syndrome is a condition where the symptoms of COVID-19 persist even though they have been declared cured. Health workers have a fairly large risk of being infected with COVID-19, as well as the risk of symptoms of Post COVID 19 Syndrome with the most complaining symptom being fatigue. The purpose of this study was to examine the effect of supervised cardiopulmonary exercise on increasing functional capacity in health workers with Post Covid-19 Syndrome. This study used an experimental research design with the sample divided into the control group and the treatment group. We provided supervised cardiopulmonary exercise with moderate and high intensity on 30 medical personnel for 12 times in Cardiac Rehabilitation Gymnasium. It was concluded that treatment group experienced an increase in functional capacity compared to the control group. The improvement in functional capacity between the moderate and high intensity exercise groups was not significantly different. Increased functional capacity will improve the quality of life in patients with Post Covid-19 Syndrome.
Co-Authors Kurniawan, Ferry D. Muhammad Ridwan Muhammad Ridwan Munirwan, Haris Teuku Heriansyah Teuku Heriansyah, Teuku