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Kemal Akbar Suryoadji
Faculty of Medicine, University of Indonesia, Jakarta, Indonesia
Health Professions Medicine & Pharmacology Public Health

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Underweight Nutritional Status as a Predictor of Mortality in Alzheimer's Disease : A Systematic Review and Meta-Analysis of Prospective Cohort Study Kemal Akbar Suryoadji; Muhammad Faruqi; Vincentius Juan Aryaputra
Cermin Dunia Kedokteran Vol 49, No 6 (2022): Nutrisi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v49i6.1884

Abstract

Purpose: The research was conducted to determine the risk of mortality in underweight Alzheimer's disease patients and to consider nutritional maintenance as an important management approach in Alzheimer’s patients. Methods: This review used publications found in Pubmed, Scopus, Cochrane, and ScienceDirect. The keywords were “((Alzheimer's Diseased) AND (Underweight) AND (Mortality))”. Meta-analysis review with Revman 5 software calculated the average relative risk from all selected cohort studies. Result: The process identify 230 articles, only three studies with 1423 patients were included. The meta-analysis result showed that based on their BMI status, underweight patients have a higher risk of mortality than normal weight patients. (RR: 1.65, 95% CI: 1.32-2.06). Conclusion: Underweight nutritional status in Alzheimer's patients increases the risk of mortality compared to the individuals with normal nutritional status.Tujuan: Penelitian ini dilakukan untuk menentukan risiko kematian pasien penyakit Alzheimer yang memiliki berat badan kurang dan mempertimbangkan pemeliharaan nutrisi sebagai bagian dari pendekatan tata laksana pasien Alzheimer. Metode: Tinjauan dalam publikasi ini diambil dari Pubmed, Scopus, Cochrane, dan ScienceDirect. Kata kunci yang digunakan ialah “((Alzheimer Diseased) AND (Underweight) AND (Mortality))”. Tinjauan meta-analisis menggunakan perangkat lunak Revman 5 menghitung rata-rata risiko relatif dari semua studi kohort yang dipilih. Hasil: Dari 230 artikel yang berhasil diidentifikasi, 3 studi dengan 1423 pasien dimasukkan dalam studi. Hasil meta-analisis menunjukkan berdasarkan status Indeks Massa Tubuh, bahwa pasien dengan berat badan kurang memiliki risiko mortalitas lebih tinggi daripada pasien dengan berat badan normal (RR: 1.65, 95% CI: 1.32-2.06). Simpulan: Kondisi nutrisi dengan berat badan kurang pada pasien Alzheimer meningkatkan risiko mortalitas dibandingkan dengan individu yang memiliki berat badan normal.
Underweight Nutritional Status as a Predictor of Mortality in Alzheimer’s Disease: A Systematic Review and Meta-Analysis of Prospective Cohort Study Kemal Akbar Suryoadji; Muhammad Faruqi; Vincentius Juan Aryaputra
Cermin Dunia Kedokteran Vol 49 No 6 (2022): Nutrisi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v49i6.245

Abstract

Purpose: The research was conducted to determine the risk of mortality in underweight Alzheimer’s patients and consider nutritional maintenance as an important management approach in Alzheimer’s patients. Methods: This review used publications found in Pubmed, Scopus, Cochrane, and ScienceDirect. The keywords were “((Alzheimer’s Diseased) AND (Underweight) AND (Mortality))”. A meta-analysis review with Revman 5 software calculated the average relative risk from all selected cohort studies. Result: The process identified 230 articles; only three studies with 1423 patients were included. The meta-analysis result showed that underweight patients have a higher risk of mortality than normal weight patients based on their BMI status. (RR: 1.65, 95% CI: 1.32-2.06). Conclusion: Underweight nutritional status in Alzheimer’s patients increases the risk of mortality compared to the individuals with normal nutritional status. Tujuan: Penelitian ini dilakukan untuk menentukan risiko kematian pasien penyakit Alzheimer yang memiliki berat badan kurang dan mempertimbangkan pemeliharaan nutrisi sebagai bagian dari pendekatan tata laksana pasien Alzheimer. Metode: Tinjauan dalam publikasi ini diambil dari Pubmed, Scopus, Cochrane, dan ScienceDirect. Kata kunci yang digunakan ialah “((Alzheimer Diseased) AND (Underweight) AND (Mortality))”. Tinjauan meta-analisis menggunakan perangkat lunak Revman 5 menghitung rata-rata risiko relatif dari semua studi kohort yang dipilih. Hasil: Dari 230 artikel yang berhasil diidentifikasi, 3 studi dengan 1423 pasien dimasukkan dalam studi. Hasil meta-analisis menunjukkan berdasarkan status indeks massa tubuh, bahwa pasien dengan berat badan kurang memiliki risiko mortalitas lebih tinggi daripada pasien dengan berat badan normal (RR: 1,65; 95% CI: 1,32-2,06). Simpulan: Kondisi nutrisi dengan berat badan kurang pada pasien Alzheimer meningkatkan risiko mortalitas dibandingkan dengan individu yang memiliki berat badan normal.
Underweight Nutritional Status as a Predictor of Mortality in Alzheimer’s Disease: A Systematic Review and Meta-Analysis of Prospective Cohort Study Kemal Akbar Suryoadji; Muhammad Faruqi; Vincentius Juan Aryaputra
Cermin Dunia Kedokteran Vol 49 No 6 (2022): Nutrisi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v49i6.245

Abstract

Purpose: The research was conducted to determine the risk of mortality in underweight Alzheimer’s patients and consider nutritional maintenance as an important management approach in Alzheimer’s patients. Methods: This review used publications found in Pubmed, Scopus, Cochrane, and ScienceDirect. The keywords were “((Alzheimer’s Diseased) AND (Underweight) AND (Mortality))”. A meta-analysis review with Revman 5 software calculated the average relative risk from all selected cohort studies. Result: The process identified 230 articles; only three studies with 1423 patients were included. The meta-analysis result showed that underweight patients have a higher risk of mortality than normal weight patients based on their BMI status. (RR: 1.65, 95% CI: 1.32-2.06). Conclusion: Underweight nutritional status in Alzheimer’s patients increases the risk of mortality compared to the individuals with normal nutritional status. Tujuan: Penelitian ini dilakukan untuk menentukan risiko kematian pasien penyakit Alzheimer yang memiliki berat badan kurang dan mempertimbangkan pemeliharaan nutrisi sebagai bagian dari pendekatan tata laksana pasien Alzheimer. Metode: Tinjauan dalam publikasi ini diambil dari Pubmed, Scopus, Cochrane, dan ScienceDirect. Kata kunci yang digunakan ialah “((Alzheimer Diseased) AND (Underweight) AND (Mortality))”. Tinjauan meta-analisis menggunakan perangkat lunak Revman 5 menghitung rata-rata risiko relatif dari semua studi kohort yang dipilih. Hasil: Dari 230 artikel yang berhasil diidentifikasi, 3 studi dengan 1423 pasien dimasukkan dalam studi. Hasil meta-analisis menunjukkan berdasarkan status indeks massa tubuh, bahwa pasien dengan berat badan kurang memiliki risiko mortalitas lebih tinggi daripada pasien dengan berat badan normal (RR: 1,65; 95% CI: 1,32-2,06). Simpulan: Kondisi nutrisi dengan berat badan kurang pada pasien Alzheimer meningkatkan risiko mortalitas dibandingkan dengan individu yang memiliki berat badan normal.
Prognosis Mortalitas Pasien Tuberkulosis dengan Komorbid Diabetes Melitus Tipe 2: Analisis Kemal Akbar Suryoadji; Ahmad Fauzi; Alifaturrasyid Syafaatullah Ridwan; Abdul Hafiidh Surya Putra; Wismandari Wisnu
Cermin Dunia Kedokteran Vol 52 No 2 (2025): Pediatri
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i2.1248

Abstract

Introduction: Indonesia ranks 3rd in tuberculosis (TB) cases in the world, and data from the Ministry of Health in 2020 showed that 10%-15% of TB sufferers had diabetes mellitus (DM). TB is one of the important causes of death, and DM affects the immune system which can increase the severity and mortality of the disease. This evidence-based case report was conducted to examine the mortality risk of tuberculosis patients with DM comorbidity. Methods: An article search was conducted to answer research questions based on 3 databases: PubMed, Cochrane, and ScienceDirect with the keywords “((Tuberculosis) AND (DM type 2) AND (Mortality))”. The search was based on inclusion and exclusion criteria and a critical review was conducted according to the guidelines for prognostic studies. Result: Tuberculosis patients with type 2 DM comorbidities have a 1.51 times higher risk of mortality compared to tuberculosis patients without type 2 DM comorbidities. Conclusion: Study by Huangfu, et al, (2019) can be the best choice to answer the clinical question that the risk of death of tuberculosis patients with comorbid DM increases by 1.51 times compared to patients without DM.
Co-Authors Abdul Hafiidh Surya Putra Ahmad Fauzi Alifaturrasyid Syafaatullah Ridwan Muhammad Faruqi Vincentius Juan Aryaputra Wismandari Wisnu