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PENGARUH PEMBERIAN BISPENOL-A (BPA) TERHADAP JUMLAH SPERMATOZOA PADA Rattus norvegicus GALUR WISTAR ALBINO Tetra Anestasia Putri
JURNAL KESEHATAN PERINTIS Vol 6 No 1 (2019): JUNI 2019 : Jurnal Kesehatan Perintis (Perintis's Health Journal)
Publisher : LPPM UNIVERSITAS PERINTIS INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (501.31 KB) | DOI: 10.33653/jkp.v6i1.210

Abstract

Bispenol-a (BPA) has an esterogen hormone activity while it enters the body, it can become endocrine disruptor. The objetive of this study was to purpose to prove that bispenol a can decrease spermatozoa cell count in male wistar albino strain rats (rattus novergicus).This research is an experimental design with post-only control group by using 20 male wistar albino strain rats (rattus Novergicus). Those sample aged 2-3 months which divided into four groups for 5 rats each. Control group (K) without bispenol-a adduction. The first (P1), second (P2), and third (P3) group treatment was given with BPA in 51 days for 0.45, 0.9 and 1.8 mg/body weight(kgs)/day for a 51-day. After 51-day treatment.This research showed that mean value of testosterone hormone for control group was 7.78 ng/lts. P1 group, P2 and P3 groups showed 6.19, 5.23 and 4.02 ng/lt.the count of spermatozoa has mean value for control group was 39,1 while first group (P1) was 30.2 . In second (P2) and third (P3) treatment group were 21,1 and 19.7. Data analysis showed mice spermatozoa cell count had p <0.05, which means that there is significance differentiation between control and treatment groups.It can be concluded that there is an effect of bisphenol a adduction on male Rattus novergicus wistar albino strain spermatozoa cell count.
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