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ASPEK MOLEKULER MALARIA BERAT Putu Indah Budi Apsari
WICAKSANA: Jurnal Lingkungan dan Pembangunan Vol. 3 No. 1 (2019)
Publisher : Lembaga Penelitian, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wicaksana.3.1.2019.49-53

Abstract

Malaria adalah salah satu dari penyakit yang mengancam jiwa di dunia, lebih dari jutaan manusia setiap tahun. Plasmodium palcifarum adalah parasit malaria yang paling sering menyebabkan penyakit yang berat. Beberapa menit setelah parasit ditransmisikan ke dalam tubuh manusia lewat gigitan nyamuk (dalam bentuk sporozoit) parasit menginvasi sel hepatosit tempat parasit dapat memperbanyak diri dengan cepat. Ribuan merozoit keluar dari hepar kemudian menginvasi sel darah merah. Pada malaria berat terjadi proliferasi parasit di dalam sel darah merah kemudian seldarah merah terinfeksi melekat pada lapisan endotel (cytoadherence) dan melekat pada sel darah merah yang tidak terinfeksi (rosetting). Pengetahuan tentang aspek molekuler malaria berat dapat membantu para peneliti dan klinisi dalam rangka mengurangi morbiditas dan mortalitas yang disebabkan oleh malaria berat. Keyword: malaria berat, molekuler, Plasmodium
Manajemen Luka Bakar Kornea: Literature Review I Gusti Ngurah Kezawa Arisurya; I Gusti Putu Okta Santu Prastya; Ketut Ayu Restu Saptrianing Tyas; Putu Indah Budi Apsari
Aesculapius Medical Journal Vol 4 No 3 (2024): October
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.4.3.2024.366-369

Abstract

Corneal burns are complex eye injuries that require innovative strategies for effective management. Eye burns related to exposure can be categorized into chemical burns (acid and alkali burns), radiation burns from ultraviolet (UV) sources, and thermal burns. Alkaline corneal injuries are more common than acidic due to the prevalence of household cleaning agents containing ammonia and alkali. Acid burns are usually work-related injuries involving industrial processes, but can also be intentional attacks. The clinical manifestations of corneal burns involve several main symptoms that indicate the severity of the injury. Such pain interferes with daily activities and causes significant discomfort, requiring immediate medical attention. Successful management of corneal swelling and injury has been achieved through methods such as Dex-NW, cross-linked hyaluronic acid, antioxidant Tualang honey, sodium hyaluronic acid and topical vitamin c treatment.
Perbedaan Tingkat Kecemasan Ibu Bersalin di RSD Mangusada setelah Pemberian Teknik Distraksi Musik Klasik Dewa Gede Adrian Harta Wiguna; I Gusti Ngurah Made Bayuningrat; Putu Indah Budi Apsari; I Made Pariartha; Ni Putu Indah Kusumadewi Riandra
Aesculapius Medical Journal Vol 5 No 2 (2025): June
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.5.2.2025.150-158

Abstract

The maternal mortality rate in Indonesia is one of the highest in the world. According to WHO, in 2017, 830 mothers in the world died due to complications that occurred during pregnancy and childbirth. One of the main factors causing maternal death according to WHO are prolonged labor. This research determine the differences in anxiety levels of mothers in the first stage of latent phase labor at the Mangusada Hospital after administering classical music distraction. Through this research, we can also determine the level of anxiety among mothers giving birth at the Mangusada Hospital using the PRAQ-R2 instrument which is valid and reliable. This research design uses quantitative research methods with an experimental and one group pretest posttest design. The sample in this study was all women giving birth in the first stage of the latent phase at the Mangusada Hospital from July to September with a total of 40 people. Univariate analysis showed that the majority of mothers were 25 years old, primiparous, with a gestational age of 38 weeks. Then the difference anxiety level measured using a non-parametric test, namely Wilcoxon Sign Rank Test. Wilcoxon showed a significant reduction in anxiety levels in mothers in the first stage of labor after being given treatment. This is proven by the value p < 0.001. Based on the results of the analysis, there were differences in the anxiety levels of mothers in the first stage of latent phase labor at the Mangusada Hospital after giving classical music distraction techniques.