Daniel Mahendrakrisna
Dokter Umum, RSUD Kota Surakarta, Surakarta, Indonesia

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Keracunan Tanaman Kecubung Daniel Mahendrakrisna; Khadijah Nur Al Firdausi
Cermin Dunia Kedokteran Vol 47, No 11 (2020): Infeksi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v47i11.1196

Abstract

Keracunan tanaman Datura stramonium atau yang dikenal sebagai tanaman kecubung perlu mendapatkan perhatian. Tanaman ini mudah ditemukan; dapat disalahgunakan sebagai zat psikotropika. Gejala klinis kasus ini adalah gejala peningkatan saraf parasimpatis berupa midriasis, kulit kering, takikardia. Tatalaksana keracunan tanaman Kecubung suportif, umumnya akan membaik sendiri; jika berat dapat diberi reversible cholinesterase inhibitor seperti physostigmine.Datura stramonium, known as Kecubung flower in Indonesia, is a plant often used as a medicine; this plant is also often abused as psychotropics. The clinical symptoms in this case are increased parasympathetic activities such as mydriasis, dry skin, and tachycardia. Datura intoxication treatment is supportive. In severe cases, reversible cholinesterase inhibitor such as physostigmine should be used.
Karakteristik Pasien Stroke Usia Muda di RSUD Kota Surakarta Daniel Mahendrakrisna; Drestha Pratita Windriya; Aria Chandra GTS
Cermin Dunia Kedokteran Vol 46, No 3 (2019): Nutrisi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v46i3.502

Abstract

Latar Belakang. Kejadian stroke pada usia muda kurang dari 5% dari seluruh kejadian stroke. Beberapa penelitian melaporkan peningkatan angka kejadian stroke pada usia kurang dari 45 tahun. Penelitian ini untuk mengetahui angka kejadian dan karakteristik pasien stroke usia muda di RSUD Kota Surakarta. Metode. Penelitian deskriptif observatif pada populasi semua penderita stroke usia muda (18-45 tahun) di RSUD Kota Surakarta dari bulan Januari 2017 hingga Juni 2018. Data diambil dari rekam medis berupa usia, jenis kelamin, jenis stroke, hasil CT scan, serta faktor risiko. Hasil. Dari 420 pasien stroke pada rentang waktu Januari 2017-Juni 2018, didapatkan 28 penderita stroke usia muda, rerata usia 39.6 tahun dengan rentang usia 29 sampai 45 tahun, 53.6 % laki-laki, 78.6% menderita stroke non hemoragik, 39.3% menderita kelemahan sisi kanan. Didapatkan riwayat hipertensi pada 85.7%, diabetes mellitus pada 14.3%, hiperkolesterolemia 17.9%, hiperurisemia 21.4%, gagal jantung 7.1%, epilepsi 7.1%, dan riwayat stroke 3.6%. Tidak ada yang mempunyai riwayat penyakit jantung koroner dan aritmia jantung. Simpulan. Stroke usia muda jarang, sebagian besar non hemoragik. Hipertensi dan dislipidemia juga merupakan faktor risiko utama stroke di usia muda.Introduction. Stroke in young adults is less than 5% of all incidence of stroke; but it is increasing among less than 45 years old. The purpose of this study was to determine the incidence and characteristics of young stroke patients in RSUD Kota Surakarta. Method. A descriptive analytic study on all stroke patients aged between 18-45 years in RSUD Kota Surakarta during January 2017 to June 2018. Data was collected from medical record consist of age, gender, type of stroke, CT scan data and risk factors. Result. From 420 stroke patients in the period of January 2017-June 2018, there were 28 young stroke patients in the range of 29 to 45 years old, the average was 39.6 years old; 53.6% were male and 78.6% suffered a non-hemorrhagic stroke, 39.3% had right hemiparesis. Hypertension was found in 85.7%, diabetes mellitus in 14.3%, dyslipidemia in 17.9%, high uric acid in 21.4%, heart failure in 7.1%, epilepsy in 7.1%, and previous stroke history in 3.6% patients. No patients has a history of coronary heart disease and cardiac arrhythmias. Conclusion.The young adults stroke incidence is low. Ischemic stroke is the most common type. Hypertension and dyslipidemia are the most common found stroke risk factors.
Tatalaksana Epilepsi Refrakter Daniel Mahendrakrisna; Rizaldy Taslim Pinzon
Cermin Dunia Kedokteran Vol 47, No 9 (2020): Neurologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v47i9.911

Abstract

Epilepsi refrakter atau resisten obat didefinisikan sebagai kegagalan respon terhadap dua obat anti epilepsi sesuai jadual, dosis, dan rute pemberian, baik monoterapi maupun kombinasi, untuk tercapainya bebas serangan. Serangan epilepsi yang tidak terkontrol atau resisten obat umumnya berkaitan dengan prognosis buruk, dan mengganggu kualitas hidup. Beberapa pilihan terapi kasus epilepsi refrakter yaitu Diet Ketogenik, Deep Brain Stimulator (DBS), Vagal Nerve Stimulator (VNS), Transcranial Magnetic Stimulation (TMS), Responsive Cortical Neuro-Stimulator (RNS), dan Pembedahan. Terapi lini pertama adalah pembedahan reseksi,Refractory epilepsy is defined as an epilepsy unresponsive to two or more anti epileptic drugs with proper schedule and doses, on monotherapy and combined therapy, to achieve seizures freedom. Refractory epilepsy was associated with poor prognostic and decreased quality of life. Several alternatives for refractory epilepsy are ketogenic diet, Deep Brain Stimulator (DBS), Vagal Nerve Stimulator (VNS), Transcranial Magnetic Stimulation (TMS), Responsive Cortical Neuro-Stimulator (RNS), and surgery. The first line therapy for refractory epilepsy is resection surgery.